Lecture 10 Anesthesia in Horses Flashcards
What are things you are interested when preping for horse anesthesia
- Presenting complaint
- Patient status
- Procedure
- IV catheter – jugular
- Wrap lower limbs
- Wash mouth
What premedications do you use for horses
- Alpha-2 agonist (one of the following):
- Xylazine
- Detomidine
- Romifidine
- Opoid
- Butorphanol
- Why would you use an alpha-2 agonist
- What are the onset of actions if given IV?
- Reasons:
- sedation
- anxiolysis
- adjunct analgesia
- muscle relaxation
- Onset of action 3-5 minutes (IV)
What is the onset of action and duration of action of:
- Xylazine
- Detomidine
- Romifidine
- Xylazine –
- Onset of action ~3-5 minutes,
- DOA ~30-60 minutes
- Detomidine –
- Onset of action ~5 minutes,
- DOA ~60 minutes
- Romifidine –
- Onset of action ~15 minutes,
- DOA ~2 hours
What are the cardiovascular effects of alphla-2 agonists
- Initial hypertension then hypotension
- Bradycardia,
- 2nd degree atrio-ventricular block
- P waves with no QRS
- ↓ cardiac output
- What type of opioid is butorphanol
- Why use this opoid and not others
- What is another function of butorphanol other than analgesia?
- Mu antagonist/kappa agonist
- Other opoids are less mac sparing in horses and causes excitement
- Makes horse ‘plants’ feet
- (They don’t move their and place them down)
What do you use for induction on horses
- Ketamine
- benzodiazepine
- midazolam or (this one used most commonly now)
- diazepam
- Guafenesin (GG)
- What is guafenesin?
- What side effects does it have?
- How is it administered?
- Why administered that way?
- Central muscle relaxant
- Mild CV/respiratory effects
- 5% solution in 1 liter 5% dextrose
- 10% or > causes hemolysis & thrombophlebitis
How are the induction medications given?
- Bolus guafenesin 25-50mg/kg (250-500ml/horse)
- Then bolus Ketamine + benzodiazepine (midazolam or diazepam) (KM or KD)
How are horses intubated?
Blind intubation
- Extend head/neck in lateral recumbency
- Mouth speculum
- Tongue thru interdental space
- Over tongue, past cheek teeth, thru glottis
- Resistance?
- Pull back slightly, rotate 90° & advance
- DO NOT FORCE
- Inflate ET cuff
- Ventilatory support through Demand valve – IPPV with O2
- They become hypoxic shortly after intubation
How are horses positioned
- use hoist
- position on table
- Want to have even distribution on muscles
- want to maintain blood flow
- Dont want pressure on nerves
What are different ways to administer Intra-op Analgesia
- Regional anesthesia
- Can be limited by needing use of limbs for recovery
- Constant Rate infusions
- Lidocaine
- Ketamine
- Dexmedetomidine
What Intra-op Monitoring is done in horses
- ECG
- SpO2
- EtCO2
- Inhalant agent monitoring –
- Inspired/Expired Isoflurane
- Invasive (direct) BP monitoring always
What must you remember when monitoring EtCO2 in horses
EtCO2 is 10-15 less than PaCO2
What is the minimum MAP you want to maintain in horses
70mmHg (60 in small animals)
How do you treat hypotension in horses
- IV fluids
- Multi-modal analgesia/anesthesia
- To decrease amount of isoflurane used because it decreases BP
- Dobutamine CRI
How does dobutamine work to treat hypotension?
- β1 > β2 - ↑ ↑ contractility & cardiac output, BP
- Horses have a lot of sererve so can do this
- Do not want peripheral vasoconstriciton so wont use norepinephrine and epinerphine to