Lecture 10/11 ( slide 1-67) Flashcards
What is population genetics
Study of evolution performed by modeling genetic changes in populations over time
What is a population
Group of organisms belonging to 1 species that live in a place and share a common set of genes
What is a gene pool
all of the alleles in a population
what is a genotype frequency
number of individuals with a genotype divided by all individuals in a population (reminder genotype is the AA Aa or aa designation) (see slide 12 for math example)
What is an allele frequency
number of copies of an allele in a population divided by total number of alleles in the pop. (remember that the number of alleles in a diploid population is 2x the population) (see slide 14 for math example)
Does AA always mean dominant
No. Remember this, as he had questions in exam 1 that were tricksy around this.
5 Assumptions of Hardy Weinberg
infinite population, mating is random, no mutation, no migration, no natural selection.
What does it mean if HWE is the null for your calculations
If HWE is the null, the null hypothesis is that there is no evolution occurring in the population
What is the formula for hardy weinberg equilibrium
p^2 + 2pq + q^2
How do you calculate p and q / what do p and q mean
p is the frequency of the A allele q is the frequency of the a allele (NOT GENOTYPE) - (see slide 14 for allele frequency, then begin at slide 21 for HWE math)
How is a population brought into HWE
A single round of random mating will bring a population into HWE - (but any forces acting AFTER mating/zygote formation may violate HWE)