Lecture 1- Polarity Flashcards
3 mechanisms of polarity establishment in bacteria
passive exclusion by the nucleoid
selective association with high-curvature membrane regions
diffusion of capture (polar protein already in place, another protein associates with it)
2 mechanisms of localisation following division
inheritance of proteins from the site of division, or from the sidewall as proteins from the middle of the old cell will be at the pole of the new one- automatic displacement of peptidoglycans
FtsZ
protein which assembles as a ring at the division site in E. coli
contracts using GTP, division triggered by a ‘divosome’
DivIVA
protein in B. subtilis which forms complexes at the curved regions of the membrane which form during division and remain at the new pole
example role of DivIVA
helps position the chromosomal origin of replication at the pole, mediated by a Par system, which helps DNA associate with SMCs and migrate appropriately
actually giving up lol whoever gave this lecture is EVILLLLL