Lecture 1: Introduction to Human Physiology Flashcards
What at the levels of cellular organization?
- Cells
- Tissues
- Organs
- Organ Systems
Differentiated cells with similar properties aggregate to form ________.
tissues
What is an organ composed of?
two or more kinds of tissues in various proportions and patterns
Describe an organ system and give an example
multiple organs that work together
Example: The urinary system (kidney + ureters + urethra + badder)
Name the eleven different organ systems in the body.
- Circulatory
- Digestive
- Endocrine
- Immune
- Respiratory
- Lymphatic
- Musculoskeletal
- Nervous
- Integumentary
- Reproductive
- Urinary
Primary function of which organ system?:
Transport blood throughout the body
Circulatory
Primary function of which organ system?:
Digestion and absorption if nutrients and water; elimination of wastes
Digestive
Primary function of which organ system?:
Regulation and coordination of many activities in the body. including growth, metabolism, reproduction, blood pressure, water and electrolyte balance, and others.
Endocrine
Primary function of which organ system?:
Defense against pathogens
Immune
Primary function of which organ system?:
Protection aginst injury and dehydration; defense against pathogens; regulation of body temperature
Integumentary
Primary function of which organ system?:
Collection or extracellular fluid for return to blood; participation in immune defenses; absorption of fats from digestive system
Lymphatic
Primary function of which organ system?:
Support, protection, and movement of the body; production of blood cells
Musculoskeletal
Primary function of which organ system?:
Regulation and coordination of many activities in the body; detection and response to changes in the internal and external environments; states of consciousness; learning memory emotion; others
Nervous
Primary function of which organ system?:
Production of sperm; transfer of sperm to female
Reproductive (male)
Primary function of which organ system?:
Production of eggs; provision of a nutritive environment for the developing embryo and fetus; nutrition of the infant
Reproductive (female)
Primary function of which organ system?:
Exchange of carbon dioxide and oxygen; regulation of hydrogen ion concentration in the body fluids
Respiratory
Primary function of which organ system?:
Regulation of plasma composition through controlled excretion of ions water, and organic wastes
Urinary
Muscles are specialized to ________ and generate _________
contract; force
What are the three types of muscle cells in the human body
- Cardiac muscle
- Skeletal muscle
- Smooth muscle
Which type of muscle(s) are involuntary?
cardiac and smooth muscle
Which type of muscle(s) are voluntary?
skeletal muscle
What is a neuron?
a cell of the nervous system that is specialized to initiate, integrate and conduct electrical signals to other cells
What does a collection of neurons form?
nervous tissue
Where can you find nervous tissue?
brain or spinal cord
______ form many neurons that are packaged together along with connective tissue to from a _____
axons; nerve
Where are epithelial cells located?
- Outer surfaces that cover the body or individual organs
- Inner surfaces of the tubular and hollow structures within the body
Epithelial cells are specialized for the selective _______ and _______of ions and organic molecules, and for ________
Secretion; absorption; protection
Name the type of epithelial cell:
single cell layer thick
simple
Name the type of epithelial cell:
Multiple layers thick
Stratified
Name the type of epithelial cell:
Cube shaped
Cuboidal
Name the type of epithelial cell:
Column-shaped, elongated
columnar
Name the type of epithelial cell:
Flattened
Squamous
Name the type of epithelial cell:
Possessing cilia
ciliated
What do the basolateral membranes function as in epithelial cells
Transports glucose out of cell

What does the apical membrane function in epithelial tissue?
transports glucose into cell

Connective tissue cells ________, ________, and ________ the structures of the body
connect ; anchor; support
Name all the different types of connective tissues
- Loose Connective
- Dense Connective
- Blood
- Bone
- Cartilage
- Adipose
What surrounds the cells?
extracellular fluid and extracellular matrix
What does the extracellular matrix consist of?
proteins, polysaccharides, and minerals
What are the functions of the extracellular matrix
- Provides scaffold for cellular attachments
- chemical messengers to cells to help regulate their activity, migration, growth, and differentiation
What are the proteins of the ECM made of?
collagen fibers, elastin fibers, and a mixture of nonfibrous proteins
The proteins of the ECM consist of (ropelike/rubberband-like) collagen fibers
ropelike
The proteins of ECM consist of (ropelike/rubberband-like) elastin fibers
rubberband-like
Where is intracellular fluid located?
inside the cells
The fluid in the blood is called:
extracellular fluid
The fluid surrounding cells is called:
extracellular fluid
What percent of the extracellular fluid is in the blood (plasma)?
20-25%
What percent of the extracellular fluid lies around and between cells?
75-80%
What percent of the extracellular fluid is interstitial fluid?
75-80%
Define interstitium
the space containing interstitial fluid
What makes up the total volume of extracellular fluid?
plasma and interstitial volumes
How much water (%) accounts for a human adult’s body weight?
55-60%
How much intracellular fluid (%) accounts for an adults body weight?
~67%
How much extracellular fluid (%) accounts for an adults body weight?
- How much of that percent is plasma?
- How much of that percent is interstitial fluid?
~33%
- 7%
- 26%
What does the function of most body cells depend on?
the concentrations of solutes in the intracellular and extracellular fluids
What is the extracellular concentration of Na+ ?
145 mM
What is the extracellular concentration of K+?
5 mM
What is the extracellular concentration of Ca2+
1 mM
What is the extracellular concentration of Cl- ?
100 mM
What is the intracellular concentration of Na+ ?
15 mM
What is the intracellular concentration of K+ ?
150 mM
What is the intracellular concentration of Ca2+ ?
0.0001
What is the intracellular concentration of Cl- ?
7 mM
Sodium is more concentrated in the (extracellular/intracellular) fluid
extracellular
Potassium is more concentrated in the (extracellular/intracellular) fluid
intracellular
Calcium is more concentrated in the (extracellular/intracellular) fluid
extracellular
Chloride is more concentrated in the (extracellular/intracellular) fluid
extracellular
Define Homeostasis
A state of reasonably stable balance between physiological variables
What variables are factored into homeostasis?
- blood pressure
- body temperature
- pH of extracellular fluid
- concentrations of sodium ions or glucose in the blood
variables of homeostasis stay regulated despite changes in:
- Temperature
- What has been eaten
- resting vs exercising
Homeostasis is a (static/dynamic) process
dynamic
True or False:
Physiological variables must resist dramatic change over a 24 hour period in order to keep the system in an overall balance
false
True or False
Physiological variables can change dramatically over a 24 hr period, but the system is still overall balance
True
In physiology, homeostasis (is/is not) maintained
is
In pathophysiology, homeostasis (is/is not) maintained
is not
A reflex is a(n) (voluntary/involuntary) response
involuntary
define stimulus
detectable change in the internal or external environment
Define receptor
detects the change in the internal or external environment
In a reflex arc, the receptor uses the (efferent/afferent) pathway to the:
afferent; integrating center

In a reflex arc, the integrating center uses the (afferent/efferent) pathway to the:
efferent; effector

Define effector
cell(s) whose change in activity results in a response in a control system
Define negative feedback
when the system’s response opposes the original change in the system
(brings back to homeostasis)
True or False:
A negative feedback system shuts the system off once the set point has been reached
true
True or False:
A negative feedback system enhances the production of the product.
false
True or False:
A positive feedback system enhances the production of the product
True
True or False:
A positive feedback system shuts the system off once the set point has been reached
false
Homeostasis primarily occurs through (negative/positive) feedback.
negative
True or False?
Each different cell type secrete a different chemical messenger
False
various cell types may all secrete the same chemical messenger
Also known as corrective responses.
negative feedback homeostatic responses
This is initiated after the steady state of the individual has been perturbed.
negative-feedback homeostasis