Lecture 1 Flashcards

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1
Q

What is cell division?

A

The process by which cells make more cells

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2
Q

Why does cell division occur?

A
  • Growth
  • Cell replacement
  • Healing
  • Reproduction
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3
Q

The two processes of cell division?

A

Mitosis or Meiosis

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4
Q

Mitosis

A

Occurs in hair stem cells

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5
Q

Meiosis

A

Occurs in germ or sex cells

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6
Q

What are Mitotic cells in an adult considered to be?

A

Stem Cells

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7
Q

Characteristics of Eukaryotyes

A

Genome is large and linear and DNA is in nucleus

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8
Q

Characteristics of Prokaryotes

A

Genome is small and circular and DNA is in cytoplasm

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9
Q

What does interphase consist of?

A
  1. G1 phase
  2. S phase
  3. G2 Phase
  4. G0 Phase
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10
Q

What happens in G1 (gap 1) phase?

A

Growth, cellular metabolism

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11
Q

What happens in S phase?

A

DNA replication (chromosome duplication)

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12
Q

What happens in G2 phase?

A

Preparation for Mitosis

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13
Q

What happen in M phase (mitosis)?

A

chromosomal separation and cytokinesis

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14
Q

What is Interphase?

A

The time between successive mitoses (G1 + S + G2)

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15
Q

What is quiescent?

A

Cells that are not actively dividing (entering a G0 state)

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16
Q

How many pairs of chromosomes do humans have?

A

23 Chromosomes

17
Q

How many pairs of sex chromosomes do humans have?

A

1 pair

18
Q

What are homologous chromosomes?

A

Same chromosomes before and after DNA replication

19
Q

What happens during mitotic cell division?

A

A single parent cell divides into two daughter cells

20
Q

What are the phases in order of Mitotic Cell Division?

A

Interphase, Prophase, Metaphase, Anaphase, Telephase

21
Q

What happens during prophase?

A

Chromosomes condense and centrosomes radiate microtubules and migrate to opposite poles

22
Q

What happens during pro metaphase?

A

Microtubules of the mitotic spindle attach to chromosomes

Nuclear envelope starts to break down

23
Q

What is a Kinetochore?

A

Large protein assemblies that connect chromosomes to microtubules of the mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to its daughters

24
Q

What happens during metaphase?

A

Chromosomes align in the centre of the cell (equatorial plate)

25
Q

What happens during anaphase?

A

Sister chromatids (which become individual chromosomes when the centromere splits) separate and travel to opposite poles

26
Q

What happens during telophase?

A

Nuclear envelope re-forms and chromosomes decondense

27
Q

How long do cells in culture take to complete 1 cell cycle?

A

24 hours

28
Q

In zebrafish embryo, how long does it take to undergo cell division?

A

20 minutes

29
Q

What is the major difference between cytokinesis in an animal vs plant?

A

Plants have the constriction of a cell membrane