Lecture 1: Building Blocks and Linear Polymers

Question 1

Polymer

Answer 1

Covalently linked chain on monomers

Question 2

common element

Answer 2

phosphate group (backbone)

Question 3

characteristic element

Answer 3

nucleotide base

Question 4

Branched Polymers

Answer 4

Can be done if the monomer has three joining sites

Question 5

Biopolymers conformation

Answer 5

linear so that they are easier to compact

Question 6

Asymmetric monomers

Answer 6

two joining sites of different characteristics

Question 7

Monomer of DNA

Answer 7

nucleotides

Question 8

Monomer of RNA

Answer 8

nucleotides

Question 9

Monomer of nucleic acids

Answer 9

nucleotides

Question 10

Monomer of protein

Answer 10

amino acids

Question 11

Characteristic Element of Nucleotides

Answer 11

heterocyclic base

Question 12

Nucleotide backbone

Answer 12

pentose phosphate

Question 13

phosphate bind site on ribose

Answer 13

5’

Question 14

hydroxyl bind sind on ribose

Answer 14

3’

Question 15

Addition of monomers to ribose

Answer 15

addition of 3’ hydroxyl end

Question 16

DNA vs RNA

Answer 16

DNA:
- Has no OH on 2’
- ACGT
- Deoxyribose

Question 17

Purines

Answer 17

Adenine and Guanine

Question 18

Pyrimidines

Answer 18

Cytosine Thymine and Uracil

Question 19

T vs U

Answer 19

thymine has a methyl group on its C5

Question 20

Linkage of two nucleotides

Answer 20

phosphodiester

Question 21

Characteristic element of amino acids

Answer 21

R variable grp

Question 22

Groups in amino acid

Answer 22

Amino grp (NH2)
Carboxylic acid grp (COOH)
R variable

Question 23

Chain growth in amino acids

Answer 23

COOH

Question 24

Amino Acids

Answer 24

Building blocks of proteins
- 8 hydrophobic 9 hydrophilic and 3 special

Question 25

Amino Acid Linkage

Answer 25

Peptide bond

Question 26

Nucleoside

Answer 26

Ribose and base

Question 27

Nucleotide Monomers

Answer 27

dNTPs

Question 28

Monomer incorporation into polymer chain

Answer 28

Amino-acyl tRNA esters

Question 29

DNA

Answer 29

Double stranded Anti-parralel Right handed helix (B) Sugar-phosphate backbone on outside Minor and Major groove

Question 30

DNA melting

Answer 30

High temp causes denaturation Increase GC content increase Tm

Question 31

Why are GC bonds stronger than AT

Answer 31

3 hydrogen bonds vs 2