Lecture 1

Question 1

Human cells express 20% of their genes

Answer 1

True

Question 2

Proteins are mutated

Answer 2

False. Genes are mutated. The product is an aberrant protein

Question 3

The central dogma is DNA to RNA to amino acids

Answer 3

True

Question 4

Genes can be switched on and off depending on the cells needs

Answer 4

True

Question 5

Clb2 was originally found in a yeast

Answer 5

True. Saccharomyces

Question 6

The domain in clb2 controls movement between nucleus and mitochondria

Answer 6

False. The nucleus and cytosol

Question 7

The correct order of mitosis is prophase metaphase telophase anaphase

Answer 7

False. Prophase metaphase anaphase telophase

Question 8

Initiation of m phase occurs due to cyclin B-cdc2 complex

Answer 8

True

Question 9

Exit of m phase occurs due to cyclin E-CDK2 complex

Answer 9

False. It’s the cyclin D-CDK4/6 complex

Question 10

Initiation of S phase uses cyclin E-CDK2 complex

Answer 10

True

Question 11

Cyclins are present for the full length of a phase

Answer 11

False. They may not be

Question 12

Checkpoint G1 is used to check for nutritional status of a cell

Answer 12

True

Question 13

Checkpoint G2 is used to ensure chromosomes are attached to the spindle

Answer 13

False. It checks mutations and ensures the copy is correct

Question 14

Mitosis checkpoint checks for mutations and ensures the copy is correct

Answer 14

False. It ensures chromosomes are attached to the spindle.

Question 15

Tubules are made of myosin.

Answer 15

False. Actin

Question 16

Cyclin b rapidly increases during mitosis to enable anaphase

Answer 16

False. It decreases to enable anaphase

Question 17

Cyclin B facilitates cytokinesis

Answer 17

True

Question 18

Kinases usually phosphorylate proteins

Answer 18

True

Question 19

Cyclin dependant kinases are enzymes

Answer 19

True

Question 20

CDKs must be bound to cyclins to become activated

Answer 20

True

Question 21

The NES helps cyclin E shuttle between the nucleus and cytoplasm

Answer 21

False. It’s cyclin B

Question 22

Site directed mutagenesis uses oligonucleotide primers that are 50-70 base pairs long

Answer 22

False. They are 10-30 base pairs long

Question 23

pP2189 has ampicillin resistance

Answer 23

True