Lecture 1 Flashcards
How many litres of blood in the body? (Adult and newborn)
5L in adult
300mL in newborn infant
How much blood circulates per day?
14,000L
Circulation time?
1 minute
How much blood per beat?
70mL
What is angiography?
The real time display of heart arteries using dye pumped through a catheter inserted in the groin.
Blood functions
Transportation of oxygen, carbon dioxide, nutrients, wasted and hormones
Regulation of temperature, pH and salinity
Protection- Leakage control system: blood clotting and - Immune system: surveillance circuit, white blood cells and antibody molecules
Components of Blood
55% plasma:
91.5% water and 7% proteins (albumins 54% and globulins 38%)
45% formed elements:
More than 99% red blood cells, white blood cells (70% neutrophils and 22% lymphocytes)
Erythrocytes
RBC
5-6 million per microL of blood
Transport 02 and C02
Leukocytes
WBC
5000-10000 per microL of blood
Defence and immunity
Basophil, eosinophil, lymphocyte, neutrophil, monocyte
Platelets
250000-400000 per microL of blood
Blood clotting
Plasma - Water function
Solvent for carrying other substances
Plasma - Ions functions
Na+, K+, Ca2+, Mg2+, Cl-, HCO3+
Osmotic balance
pH buffering
Regulation of membrane permeability
Plasma - plasma proteins functions
Albumin: Osmotic balance and pH buffering Fibrinogen: Clotting Immunoglobulin (antibodies): Defence
Plasma - substances transported by blood
Nutrients (glucose, fatty acids, vitamins)
Waste products of metabolism
Respiratory gases (O2 and CO2)
Hormones