Lecture 1 Flashcards
Axial Skeleton Endochondral Derivatives
- Vertebral Column
- Ribs
- Sternum
Appendicular Skeleton Endochondral derivatives
- Limbs
Mixed endochondral and intramembranous derivatives
- Skull
- Clavicles
Endochondral derivatives in Skull
- Cranial base and sensory capsules
- Ear ossicles and laryngeal cartilage
Intramembranous derivatives of skull
- Cranial Vault
- Face
Intramembranous Bone Growth
Spreading of bone spicules
“Soft Spot”
Anterior fontanelle
Skull stops growing at what age?
5-7 years
Endochondral Bone Formation
- Mesenchyme condenses
- At primary center, Chondrocytes differentiate and form cartilage
- Chondrocytes mineralize
- Osteoblasts follow nutrient artery and bind to mineralized matrix
- Secondary centers start ongoing growth
When does the diaphyses ossify?
By birth
Formation of interverterbral discs
Sclerotomes and notochord
8 cervical nerves and 7 cervical vertebrae
Lose half a sclerotome at skull base and another at T1
Myoblasts
- Muscle precursors
- develop from mesoderm
Splanchnic mesoderm
Gives rise to smooth muscle
Muscle precursors rising from ectoderm
- Iris
- Mammary Glands
- Sweat Glands