Lecture 1 Flashcards

1
Q

Axial Skeleton Endochondral Derivatives

A
  • Vertebral Column
  • Ribs
  • Sternum
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2
Q

Appendicular Skeleton Endochondral derivatives

A
  • Limbs
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3
Q

Mixed endochondral and intramembranous derivatives

A
  • Skull

- Clavicles

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4
Q

Endochondral derivatives in Skull

A
  • Cranial base and sensory capsules

- Ear ossicles and laryngeal cartilage

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5
Q

Intramembranous derivatives of skull

A
  • Cranial Vault

- Face

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6
Q

Intramembranous Bone Growth

A

Spreading of bone spicules

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7
Q

“Soft Spot”

A

Anterior fontanelle

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8
Q

Skull stops growing at what age?

A

5-7 years

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9
Q

Endochondral Bone Formation

A
  • Mesenchyme condenses
  • At primary center, Chondrocytes differentiate and form cartilage
  • Chondrocytes mineralize
  • Osteoblasts follow nutrient artery and bind to mineralized matrix
  • Secondary centers start ongoing growth
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10
Q

When does the diaphyses ossify?

A

By birth

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11
Q

Formation of interverterbral discs

A

Sclerotomes and notochord

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12
Q

8 cervical nerves and 7 cervical vertebrae

A

Lose half a sclerotome at skull base and another at T1

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13
Q

Myoblasts

A
  • Muscle precursors

- develop from mesoderm

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14
Q

Splanchnic mesoderm

A

Gives rise to smooth muscle

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15
Q

Muscle precursors rising from ectoderm

A
  • Iris
  • Mammary Glands
  • Sweat Glands
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16
Q

Paraxial Mesoderm

A

Gives rise to skeletal muscle

17
Q

Somitomeres

A

Give rise to muscles in the head

18
Q

Epaxial muscles

A

Form extensors of the neck and trunk

19
Q

Hypaxial muscles

A

Form the rest of axial and limb muscles

20
Q

Cervical Hypaxial musculature

A
  • Neck flexors

- Hyoid muscles

21
Q

Thoracic Hypaxial musculature

A

Flex and bend trunk

22
Q

Lumbar Hypaxial musculature

A

Hip Flexor

23
Q

Sacrococcygeal Hypaxial musculature

A
  • Pelvic diaphragm

- Striated muscle of perineum

24
Q

Limps Hypaxial musculature

A

Flexors and extensors

25
Q

FGF-10

A
  • Signal molecule from lateral plate mesoderm

- Begins limb formation at Apical Ectodermal Ridge

26
Q

Segment Separation

A
  • Constrictions at wrist and elbow

- Division of Apical ectodermal ridge and apoptosis in between digits

27
Q

First Wave of innervation

A

Motor neurons

28
Q

Second wave of innervation

A

Sensory neurons (Schwann cells)

29
Q

Dorsal Primary Ramus

A

Only epaxial and skin around back

30
Q

Upper limb rotation

A

90 degree lateral

31
Q

Lower limb rotation

A

90 degree medial

32
Q

Somatic lateral plate mesoderm

A

Bone and Vessels

33
Q

Myotome

A

Muscle

34
Q

Formation of melanocytes

A

Neural crest cells

35
Q

Formation of nerves

A
  • Motor - Neural tube

- Sensory - Neural crest