Lecture 1 Flashcards

0
Q

What is external respiration?

A

Gas exchange where air is drawn into body and air expelled from lungs to external environment

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1
Q

What is internal respiration?

A

Intracellualr mechanisms where O2 is used and CO2 is produced

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2
Q

What are the four steps in external respiration?

A

Ventilation- gas exchange between atmosphere and air sacs in lungs
Gas exchange of O2 and CO2 between air in alveoli and blood in pulmonary capillaries
Binding and transport of O2 and CO2 in blood
Exchange of O2 and CO2 between systemic capillaries and body cells

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3
Q

Explain ventilation

A

Air moving between atmosphere and alveolar sacs
Air flows down pressure gradient from h to l
Intra alveolar pressure less than atmospheric pressure during inspiration
Thorax and lungs expand
Contraction of inspiration muscles

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4
Q

What is bottles law?

A

At constant volime the pressure is inversely proportional

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5
Q

How do the lungs adhere to thorax?

A

Intrapleural fluid cohesiveness- water in intrapleural fluid attracted to each other this pleural membranes stick together.
Negative pleural pressure- pressure gradient across whole lung wall and chest wall. Lungs expand outwards whilst chest squeezed inwards

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6
Q

What does pneumothorax do?

A

Abolishes transmittal pressure gradient needed for lung expansion

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7
Q

Is inspiration active or passive?

A

Active

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8
Q

What is resting expiration, active or passive

A

Passive

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9
Q

What are the inspiration muscles used during normal resting breathing?

A

Intercostal muscles

Diaphragm

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10
Q

What nerves control the diaphragm?

A

Sphrenic- 345

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11
Q

How do you make the intra alveolar pressure fall?

A

Increased size in lungs

Air molecules contained in large space

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12
Q

why does recoil occur?

A

Due to its elastic properties

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13
Q

How does recoil of lungs make the intra alveolar pressure rise?

A

Elastic connective tissue in lungs and alveolar surface tension- this resists stretching if lungs

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14
Q

What is pneumothorax?

A

A puncture in the chest wall results in collapsed lung

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15
Q

What is law of Laplace?

A

Small alveolar have higher tendency to collapse

16
Q

What is pulmonary surfactant?

A

Mixture of lipids and proteins which lowers surface tension of smaller alveoli more than larger alveoli. This prevents smaller alveoli from collapsing

17
Q

What forces keep alveoli open?

A

Transmural pressure gradient
Pulmonary surfactant
Interdependence

18
Q

What forces promote collapse of lungs

A

Elasticity stretched
Pulmonary connective tissue
Surface tension