Lecture 1 Flashcards
0
Q
Generation of reactive species
A
Acetaminophen
1
Q
Disruption of enzyme metabolism
A
Caffeine
2
Q
Ionic imbalance or membrane leak
A
Verapamil
3
Q
Protein, lipid, or DNA modifications
A
Azathioprine
4
Q
Immune and inflammatory response
A
Penicillin
5
Q
Alteration of signal transduction
A
Atropine
6
Q
Induction of apoptosis and necrosis
A
Streptomycin
7
Q
Adverse effect
A
Of the drug
8
Q
Adverse reaction
A
Of the patient to the drug
9
Q
Adverse event
A
Negative outcome while taking a drug but not due to the drug
10
Q
Category A
A
Dose related
Common
Predicted
11
Q
Category B
A
Non dose related
Uncommon
Unpredictable
High mortality
12
Q
Category C
A
Dose and time related
Uncommon
Builds up slowly over time
13
Q
Category D
A
Time related
Uncommon
Sudden and dramatic onset after a variable delay
14
Q
Category E
A
Withdrawal
Uncommon
After removal of the drug
