Lecture 1 Flashcards
Parasitism
A type of symbiotic association between two species where one benefits (the parasite) by exploiting the resources of the other (the host)
____ ____ (the parasite) must be ____ between hosts, and the harm inflicted manifests as an illness or “disease”.
Infectious agent; transmissible
Endoparasites
Parasites that complete some or all of their life cycle within host tissues or cells
Two types of endoparasites
Microparasites and macroparasites
Microparasites (or pathogens)
Microscopic parasites characterized by high rates of reproduction directly within their hosts, usually inside host cells
Viruses
Composition: RNA/DNA encapsulated within a protein coat
Size: ~20 — 300nm (need electron microscope to observe)
Reproduction: “hijack” host cellular machinery, cannot reproduce independently (which is why they are not categorized as living things)
Reproduction speed: Extremely rapid
Examples: West Nile virus, Ebola, SARS, Measles
Bacteria
Classification: Prokaryotes (living organism)
Size: ~1–5um (can be viewed with a light microscope)
Several forms available:
- Rods (bacilli)
- Spheres (cocci)
- Spiral (spirochetes)
Examples: Lyme disease, Anthrax, Typhoid fever, Cholera, Salmonella
Protozoa
Classification: Unicellular eukaryotes (“animal-like” protists)
Size: 5–15um (can be viewed with a light microscope)
Examples: Malaria, Giardia, Leishmaniasis
Macroparasites
Parasites that are visible with naked eye and has longer generation times (primarily “helminths” — parasitic worms)
Major and minor taxa of Microparasites
*3 Major taxa:
- Viruses
- Bacteria
- Protozoa
Minor ones:
- Fungi
- Prions
Major taxa of macroparasites
- Nematodes (roundworms)
Ex. River blindness - Trematodes (flatworms)
Ex. Schistosomiasis - Cestodes (tapeworms)
Ex. Echinococcus
Ectoparasites
Parasites that live on the surface of their hosts
Ex. Ticks, mites, fleas, mosquitoes, leeches
Direct disease transmission
Physical or close contact between hosts allow disease agent to transfer from an infected host to an uninfected one.
Indirect disease transmission
Transfer of a disease agent from an infected host to an uninfected one facilitated by an intermediate host or a vector.
The 3 ecological origin of infectious diseases
- Zoonotic: Only transmit from animals to humans
- Multi-host: Transmit between both animals and humans
- Human-specific: Transmit human-to-human