Lecture 1 Flashcards

1
Q

What does the term (Pharmakon) mean?

A

Drug

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2
Q

Logos mean ?

A

Science

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3
Q

the study of substances that interact with living systems through chemical processes is ?

A

Pharmacology

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4
Q

How the substances interact with living systems through chemical processes ?

A

by binding to regulatory molecules and activating or inhibiting normal body processes

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5
Q

A term of varied usage is ?

A

Drug

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6
Q

any substance with the potential to (prevent) or (cure )disease or (enhance) physical or (mental) welfare

A

Medicine

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7
Q

any “chemical agent” that ((alters)) the -biochemical- or -physiological- processes of tissues or organisms (a substance that is listed in the pharmacopeia).

A

Pharmacology

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8
Q

((A book)) describing drugs, chemicals, and medicinal preparations

A

Pharmacopeia

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9
Q

What is the main goal of drug treatment ? OR …. The Major Objective of drug treatment is :

A

1-have a drug at the site of action.
2-proper concentration.
3-good enough to reverse a defect without producing side or toxic effects.

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10
Q

There are many ways to classify drugs , Name five of these ways😊:

A

1- Pharmacological category.
2- Physiological system targeted by the drugs.
3- Chemical nature.
4-Drug source.
5-Drugs to treat common vs. rare diseases.

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11
Q

Give me the ways that aren’t mentioned in the previous question:

A

1- The need for prescription
2- Therapeutic use

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12
Q

Give me an Examples of Natural Drug Sources :

A

1- Plants , 2- animals , 3-human , 4-Micro organisms

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13
Q

Penicillin, streptomycin and many other antibiotics is an examples of ?

A

Micro organisms

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14
Q

Give me two examples of minerals drug Sources ?

A

1-Liquid
2-paraffin

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15
Q

The need for prescription can be divided into two main parts, mention them

A

A. Prescription drugs
B. OTC drugs

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16
Q

(OTC) Abbreviation to ?

A

Over The Counter

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17
Q

OTC Can be sold over the counter with prescription (T/F)

A

FALSE

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18
Q

Are used under only medical supervision and dispensed by an order of medical practitioner only is the :

A

Prescription drugs

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19
Q

Anti-hypertensive drugs , Anti-microbial drugs , Anesthetics and hypoglycemic drugs , is an example of ?

A

Therapeutic use

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20
Q

Give me four categories of therapeutic use😊

A

1- Anti-hypertensive drugs
2- Anti-microbial drugs
3- Anesthetics hypoglycemic drugs
4- hypoglycemic drugs

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21
Q

Which of these ways must be precise ?
A. Therapeutic use
B. Prescription drugs
C. pharmacological action
D. Chemical nature

A

C

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22
Q

Mention foure example of pharmacological action :

A

1- Atenolol
2-Furosemide
3-Amlodipine
4-Ramipril

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23
Q

The examples in previous question can use to treat?

A

high blood pressure

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24
Q

Give me two examples of Physiological systems targeted by the drug :

A

• Drugs acting on respiratory system.
• Drugs acting on gastrointestinal tract.

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25
Q

Proton pumps inhibitors is an example of :

A

pumps inhibitors

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26
Q

Selective beta-2 adrenergic receptors agonists is an example of

A

Drugs acting on respiratory system

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27
Q

How we need to use Common chemical groups or structures?

A

to classify drugs that have similarity in their pharmacological profile.

28
Q

Drugs or biological products for diagnosis/treatment/prevention of a ((rare disease or condition)), or a more common disease (endemic only in resource poor countries)

A

Orphan Drugs

29
Q

Which one of drugs is no reasonable expectation that the cost of developing and marketing it will be recovered from the sales of that drug.

A

Orphan Drugs

30
Q

يلا يا حلو ، ‏give me seven examples of Main branches of pharmacology

A

• Pharmacokinetics
• Pharmacodynamics
•Pharmacotherapy
• Pharmacogenetics
• Pharmacogenomics
• Pharmacognosy
• Pharmacoeconomics

31
Q

Give me three main branches of pharmacology that aren’t mentioned in the previous question :

A

• Toxicology
• Clinical pharmacology
• Chemotherapy

32
Q

Give me the questions that pharmacology usually answer all of them

A

1.How much of a drug to give? Dose

  1. How frequent a drug should be given? Related to the biological half-life (t1/2)

3.When to give it? Before or
after meals; at bed time, PRN…

  1. How to give it? Rout of administration
33
Q

The branch of pharmacology concerned with(( the movement of drugs)) within the body is ?

A

Pharmacokinetics

34
Q

Pharmacokinetics deals with ?

A

ADME process

35
Q

The branch of pharmacology concerned with ((the effects)) of drugs and ((the mechanism)) of their action is ?

A

Pharmacodynamics

36
Q

Drug’s plasma concentration, its response and duration of action work through?

A

Pharmacodynamics

37
Q

What the drug does to the body and how can ?
* ask this question to describe the ?

A

Pharmacodynamics

38
Q

It is the physical form of drug product that is suitable for administration to man.

A

Dosage forms

39
Q

Dosage forms contains specified dose or amount of drug in a specified quantity or unit of the formulation.(T/F)

A

TRUE

40
Q

Please , mention the foure Dosage forms 😊

A

• Solid
• Semi-solid
• Liquid
• Gas

41
Q

Give me 3 examples of Solid dosage:

A

• Tablets
• Capsules
• Powder

42
Q

Can you mention five examples of Semi-solid drugs

A

• Creams
• Ointments
• Paste
• Gel
• Suppositories

43
Q

Give me two examples of liquid dosage :

A

• Monophasic Syrup
Solution
• Biphasic Suspension Emulsion

44
Q

About Gas dosage , give me two examples :

A

• Inhalers
• Sprays

45
Q

Mention the seven main routes of administrations:

A
  1. Buccal and Sublingual
  2. Oral
  3. Inhalational
  4. Parenteral
  5. Topical
  6. Rectal
  7. Transdermal (patches)
46
Q

The dosage that use through buccal and sublingual is :

A

Solid (tablet) or liquid (spray) dosage form.

47
Q

absorbed from the buccal cavity (highly vascular) and the presence of saliva fasten the dissolution in case of tablet dosage form
(THIS process related to)?

A

Buccal and sublingual

48
Q

The advantages of Buccal and sublingual is :

A

1- Quick onset of action
2- Avoid first pass effect
3- Can be used for unconscious patients

49
Q

Give me the Features of oral dosage:

A

A. Used for local or systematic effect
B. Solid or liquid dosage forms
C. Drug absorbed from the GI tract
D. Most common

50
Q

The Advantages of use oral dosage is

A
  1. Simplest rout
  2. Self administration
51
Q

The Disadvantages of use oral dosage is :

A
  1. Slow onset of action
  2. Absorption issues
52
Q

Give me the Features of Inhalational dosage

A

1- Used for local (predominantly) or systematic
effects
2- Solid (powder), liquid or gas dosage forms
3- Mostly used for respiratory conditions such as asthma

53
Q

The advantages of use Inhalational dosage is :

A
  1. Smaller dose than oral route is used to give the same effect
  2. Lower incidence of side effects
  3. Rapid onset of action
54
Q

Drugs are given by a rout out of the alimentary canal most commonly by injections , the method name is :

A

Parenteral

55
Q

superficial injection and it is used for diagnostic tests for allergy and vaccines is ?

A

Intradermal

56
Q

injection used for drugs that cannot be given orally

A

Subcutaneous

57
Q

Which one gives quick onset and prolonged action (insulin)?

A

Subcutaneous

58
Q

Which one used for solutions (aqueous and oil) and for suspensions ?

A

Intramuscular

59
Q

injection used for aqueous solutions only (antibiotics and parenteral products)
is ?

A

Intravenous

60
Q

injection used in arthritis patients to administer corticosteroids

A

Intraarticular

61
Q

Give me two characteristics of Topical

A

• Can be cream, ointment, gel, paste or lotion for external use.
• Easy to use

62
Q

Mention four of features of Rectal :

A

—Used for local or systematic effect
—Solid, liquid or semi-solid dosage forms
—Drug absorbed from the rectum ( 3 veins)
—High bioavailability (but not 100%)

63
Q

Give me the advantages of use rectal :

A

—Can be used for vomiting of unconscious patients, children, elderly or mentally disturbed and patients with dysphagia.
—Can be used for local action
(laxatives) .

64
Q

Give me the Disadvantages to use the rectal :

A

Less convenient than oral rout

65
Q

Applied to the skin and deliver a controlled dose of a drug over a specified period of time to produce systemic effect (nicotine patches) is ?

A

Transdermal

66
Q

The branch of pharmacology that deals with the undesirable effects of chemicals on living systems, from individual cells to humans to complex ecosystems is ?

A

Toxicology