Lecture 01 - Sarcodina Flashcards
Iodamoeba büchlii: General Characteristics
Logol: brown color (big glycogen vacuole)
Small
Weak trophozoite –> mostly seen in cysts
Mononuclear in cysts and trophozoites
Big nucleolus
No chromatin grains
Endolimax nana: General Characteristics
Smallest amoeba Mononuclear trophozoite Polynuclear cyst (1-4) Mostly seen in trophozoites Differentiated from Iodamoeba büchlii by size
Entamoeba histolytica: General Charateristics
Mostly seen in warm and humid parts
Finger-like Psuedolimb from 1 point –>
Chromatoidal Body = Bar Body
Entamoeba histolytica: Trophozoite
Trophozoite: 1. Magna/hematophage 2. Minuta (smaller)
within Pathogen hematophage: RBC
Small nucleolus
Chromatin grains
Entamoeba histolytica: Trophozoite to Cyst Transformation
- Glycogen vacuole
- Bar body
Trophozoite Minuta
Entamoeba histolytica: Cyst
No nucleus
Entamoeba histolytica: Pathogenesis ?????
- genus
- malnutrition: protein deficiency, cholesterol, Fe deficiency
- IgA deficiency
- alcohol
- undefined sexual habits
- intestinal flora: E.coli (better), proteus(worse)
- culture
Entamoeba histolytica: Intestinal Amoebiasis Complication
Dysentery
Colitis
Appendicitis
Peritonitis
Entamoeba histolytica: Ameboma
Granulation of a local wound
Entamoeba histolytica: non-Intestinal Amoebiasis: Hepatic
80% in right lobe, 12% in left lobe, 8% in both lobes
- Puss-less hepatitis
- Abscess: chocolate-like sterile liquid, peritonitis, fever, sweat, chill
Entamoeba histolytica: non-Intestinal Amoebiasis: Cutaneous
Painful Red Deep ulcers with raised edges
Entamoeba histolytica: Amoebiasis Lab Tests
Non-intestinal: serology
Intestinal: stool sample test unless colitis without dysentery
Cyst passer+colitis without dysentery: serology, PCR
Entamoeba histolytica: Amoebiasis Treatment
Intestinal: dihydroxy foruate Iodoquinol Paramomycin Non-intestinal: Chloroquin Emitin family Both: Nitroemidazole family: metronidazole, oronidazole. Tinidazole, secnidazole
Entamoeba hartmani: General Charateristics
Smaller than histolytica
Entamoeba coli: General Characteristics
similar to histolytica
Round and all sided psuedolimb –> slower