Lect 7. The Ovarian Cycle, Ovulation, and Uterine Changes Flashcards
Ovulation is linked to uterine changes during (1)___
menstrual cycle
Ovulation is linked to uterine changes during menstrual cycle
→ changes driven by ____ (2 types of hormones and their origin)
follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from pituitary gland
Ovulation
The role of follicle-stimulating hormone (FSH)
stimulates development of primary follicles into secondary follicles
Ovulation
follicle-stimulating hormone (FSH) stimulates development of primary follicles into secondary follicles
→ granulosa cells respond to FSH by ____
producing estrogens
Ovulation
follicle-stimulating hormone (FSH) stimulates development of primary follicles into secondary follicles
→ ___ respond to FSH by producing estrogens
LH
granulosa cells
4 Causes of LH surge from the pituitary glands
- Oocyte to complete first phase of meiosis, creates secondary oocyte and first polar body
- Secondary oocyte initiates second phase of meiosis but arrests in metaphase; will not complete meiosis unless it is fertilized
- Stimulates granulosa cells to create progesterone
- Graafian follicle ruptures, allowing ovulation
4 Causes of LH surge from the pituitary glands
- Oocyte to complete first phase of meiosis, creates ____
- Secondary oocyte initiates second phase of meiosis but arrests in ___; will not complete meiosis unless it is ___
- Stimulates granulosa cells to create ___
- Graafian follicle ruptures, allowing ___
- secondary oocyte and first polar body
- metaphase; fertilized
- progesterone
- ovulation
4 Causes of LH surge from the pituitary glands
- Oocyte to complete ___, creates secondary oocyte and first polar body
- Secondary oocyte initiates ___ but arrests in metaphase; will not complete meiosis unless it is fertilized
- Stimulates ___ to create progesterone
- ___ ruptures, allowing ovulation
- first phase of meiosis
- second phase of meiosis
- granulosa cells
- Graafian follicle
Ovulation
The cumulus oophorus travel with it and arrange themselves into new structure called ____
corona radiata
Ovulation
The role of corona radiata
surrounding zona pellucida and oocyte
Ovulation
____ travel with it and arrange themselves into new structure, corona radiata, surrounding zona pellucida and oocyte
The cumulus oophorus
Ovulation
Granulosa cells remaining in ovary form a structure called ____, producing progesterone
corpus luteum
Ovulation
Granulosa cells remaining in ovary form a structure called corpus luteum, producing ___
progesterone
Ovulation
____ remaining in ovary form a structure called corpus luteum, producing progesterone
Granulosa cells
Ovulation
If fertilization does not occur, corpus luteum dwindles to become (1)___ and (2)___ drop precipitously
- corpus albicans
- levels of progesterone
Hormonal changes of menstrual cycle also affect the lining of the uterus
→ Is it possible?
Yes
Uterine Changes
As levels of FSH climb, granulosa cells produce (1)____(estrone and 17 β-estradiol) that induce growth of endometrium into its (2)____
- estrogens
- proliferative phase
Uterine Changes
As levels of ___ climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
FSH
As levels of FSH climb, ____ produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
granulosa cell
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol)
→ The role of estrogen to uterine changes
induce growth of endometrium into its proliferative phase
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
→ spiral arteries and glands in (1)____ of endometrium grow as endometrium becomes thicker, developing (2)____
- basal layer
- follicular layer
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
→ (1) ____ in basal layer of endometrium grow as (2)____ becomes thicker, developing follicular layer
- spiral arteries and glands
- endometrium
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
→ spiral arteries and glands in (1)____ of endometrium grow as endometrium becomes thicker, developing (2)____
Uterine Changes
Under the influence of ____, progesterone (and estrogens) from corpus luteum and promote further growth of endometrium into progestational phase, making it ready to host the fertilized oocyte
Uterine Changes
Under the influence of LH,
→ rolesof progesterone (and estrogens) from corpus luteum ?
They promote further growth of endometrium into progestational phase, making it ready to host the fertilized oocyte
Uterine Changes
Under the influence of LH,
→ progesterone (and estrogens) from corpus luteum and promote further growth of endometrium into (1)____, making it ready to host the (2)____
progestational phase
fertilized oocyte
Uterine Changes
If fertilization not occur, (1)___ drop and (2)____ close
- levels of progesterone from corpus luteum
- spiral arteries to follicular layer of endometrium
Uterine Changes
If fertilization not occur, levels of progesterone from corpus luteum drop and spiral arteries to follicular layer of endometrium close
→ What happen to follicular layer?
follicular layer becomes ischemic, dies, and is shed during menstrual phase
