Lect 1&2 MCQ Flashcards
What are pyrimidine bases?
Uracil
Thymine
Cytosine
What are purine bases?
Adenine
Guanine
Central dogma of molecular biology does not involve:
Carbohydrates
A nucleotide is not composed of
Methyl residues
what does dATP stand for?
2’-deoxyadenosine-5’-triphosphate
Principle difference between a nucleoside and a nucleotide is
Nucleosides don’t contain phosphate groups
What are strands of DNA helix held together by?
H bonds
Cellular DNA replication requires
Primase
Phosphodiester bonds are formed
5’-3’
DNA polymerase
Catalyses DNA synthesis
Requires RNA primer
Uses old strand as template
Begins at replication origin
During DNA replication the fragments made on lagging strand are
Okazaki fragments
During DNA replication, DNA ligases enzyme carries out:
Joining Okazaki fragments
The enzyme that requires ATP to break the H bonds between 2 bases to open up the DNA ahead of the replication fork is:
Helicase
Which enzyme relieves twists in DNA ahead of replication fork?
Topoisomerase
DNA replication is
Semi conservative