Lec8 Flashcards

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1
Q

Structure and function of microtubules

A

Structure thickest. Hollow tubule with globular proteins

Function maintain cell shape
Cell motility in cilia and flagella
Chromatin and organelle movement

Eg 9+2 in cilia and flagella in cells of eukaryotes
A ring of 9 doublets surround a pair of central tubules

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2
Q

Structure and function of microfilament

A

Structure thinnest. Double chain of polymers of actin

Function maintain cell shape
Muscle contraction
Cell devision
Cell motility

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3
Q

Structure and function of intermediate filament

A

Structure. Cables made of fibrous protein Many different shapes

Function. Maintain cell shape
Anchorage
Nuclear lamina

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4
Q

How many kinds of Signaling

A

Direct: cell junction and cell-cell recognition

Secreted signaling molecules :
Local signaling Paracrine signaling and synaptic signaling
Long distance signaling. Testosterone

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5
Q

3 stages of signaling

A

Reception

Transduction Phosphorylation cascade. Amplify one single signal from activated relay molecules with inactivated protein kinase to active protein and function on specific genes

Response

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6
Q

Intracelllar receptors and extra ellipse receptors

A

Intercellular receptors.
Eg testosterone

Receptors activated by hormone binding
Moves to nucleus and activated genes

Extracellular (cell surface receptors)

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7
Q

The compounds of cytoskeleton

A

Microfilament
Microtubule
Intermediate filament

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