Lec8 Flashcards
Structure and function of microtubules
Structure thickest. Hollow tubule with globular proteins
Function maintain cell shape
Cell motility in cilia and flagella
Chromatin and organelle movement
Eg 9+2 in cilia and flagella in cells of eukaryotes
A ring of 9 doublets surround a pair of central tubules
Structure and function of microfilament
Structure thinnest. Double chain of polymers of actin
Function maintain cell shape
Muscle contraction
Cell devision
Cell motility
Structure and function of intermediate filament
Structure. Cables made of fibrous protein Many different shapes
Function. Maintain cell shape
Anchorage
Nuclear lamina
How many kinds of Signaling
Direct: cell junction and cell-cell recognition
Secreted signaling molecules :
Local signaling Paracrine signaling and synaptic signaling
Long distance signaling. Testosterone
3 stages of signaling
Reception
Transduction Phosphorylation cascade. Amplify one single signal from activated relay molecules with inactivated protein kinase to active protein and function on specific genes
Response
Intracelllar receptors and extra ellipse receptors
Intercellular receptors.
Eg testosterone
Receptors activated by hormone binding
Moves to nucleus and activated genes
Extracellular (cell surface receptors)
The compounds of cytoskeleton
Microfilament
Microtubule
Intermediate filament