Lec 8&9 Flashcards
Refers to the evolutionary history of species.
Phylogeny
The study of phylogenies—that is, the study of the evolutionary relationships of species.
Phylogenetics
means of estimating the evolutionary relationships
Phylogenetic analysis
evolutionary relationship obtained from phylogenetic analysis is usually depicted as branching, tree like diagram.
Phylogenetic tree
is a branching diagram composed of nodes and Branches.
phylogenetic tree
have a node called root
Rooted trees
lack of a root node
unrooted trees
Distance based methods (Neighbour Joining (NJ) is a directly Methods.
T/F?
F, indirectly methods
involves repeated alignments from the original alignment to create many new subsets to obtain many bootstrap trees.
bootstrap method
Phylogenetics is used to assess DNA evidence presented in court cases to inform situations, e.g. where someone has committed a crime, when food is contaminated, or where the father of a child is unknown.
Forensics
Phylogenetics based on sequence data provides us with more accurate descriptions of patterns of relatedness than was available before the advent of molecular sequencing.
Classification
algorithms developed for phylogenetics have been used to develop software in other fields.
Bioinformatics and computing
Multiple sequence alignment of ………………… in rice, maize and sorghum.
heavy metal P1B-ATPase (HMA) domains
to Distinguishing between relapse and reinfection is crucial for patient counselling and to choose the most appropriate retreatment.
Objective of which application of phylogenetics?
Virus classification and response to treatment
means that the hepatitis C virus is not detected in the blood 12 weeks or more after completing treatment.
Sustained virologic response (SVR)
