Lec 10&11 Flashcards
study of the collective genomes of multiple species that grow and interact in an environmental niche.
Metagenomics
Metagenomics can be used to?
- to identify new species more rapidly.
- to analyze the effect of pollutants on the environment.
involves evaluating the effectiveness and safety of drugs on the basis of information from an individual’s genomic sequence.
Pharmacogenomics
involves screening and identifying currently healthy individuals by genome analysis at the individual level.
Predicting Disease Risk at the Individual Level
the entire set of proteins produced by a cell type
proteome
The study of the function of proteomes
proteomics.
are the final products of genes that perform the function encoded by the gene.
Proteins
set of proteins with altered expression levels
protein signature
individual protein
biomarker
- used to improve the screening and early detection of cancer.
- used to develop individualized treatment plans.
- used to predict the possibility of disease recurrence.
Applications of proteomics
provides biological and medical information to allow for individualized healthcare.
Clinical bioinformatics
- detects the presence and abundance of labeled nucleic acids in a biological sample.
- measures gene expression
microarray (Clinical bioinformatics)
is the alteration of a single nucleotide.
SNPs
has established the dbSNP
NCBI
is the study of entire genomes, including the complete set of genes, their nucleotide sequence and organization, and their interactions within a species and with other species
Genomics