Lec 12: Cerebellum Flashcards
Functional Division:
Vestibulocerebellum:
Receives input from where?
Vestibular apparatus and vestibular nuclei
Vestibulocerebellum send output to where?
vestibular nuclei
Vestibulocerebellum output reaches motor neurons via…
The vestibulospinal tracts and tracts that coordinate eye and head movements (spinal thalamic tract)
Spinocerebellum: Vermal section
receives input from where?
The spinal cord
Vestibular nuclei
Auditory and vestibular information via the brainstem nuclei
Spinocerebellum: vermal section sends output to where?
The vestibular nuclei
Reticular nuclei
Motor cortex via thalamas
Spinocerebellum: vermal section sends output to where?
The vestibular nuclei
Reticular nuclei
Motor cortex via thalamus
Spinocerebellum: Vermal section output reaches motor neurons via…
The vestibulospinal tracts
Reticulospinal tract
Medial CST
Spinocerebellum: paravermal or paramedian section receives input from where?
The spinal cord
Spinocerebellum: paravermal or paramedian section sends output to where?
The red nucleus
Motor cortex (via thalamus)
Spinocerebellum: paravermal or paramedian section output reaches motor neurons via…
The rubrospinal tract
Lateral CST
Cerebrocerebelllum receives input from where?
The cerebral cortex (via the pontine nuclei)
Cerebrocerebellum sends output to where?
The motor and premotor cortices:
- dentate nucleus and motor thalamus
Red nucleus
Cerebrocerebellum outputs reaches motor neurons via…
Lateral CST and corticobrainstem tracts
Rubrospinal Tract
Vestibulocerebellum is in what lobe?
Flocculonodular lobe
The Spinocerebellum is located in what region of the cerebellum?
Vermal and paravermal/paramedian section
Cerebrocerebellum is located in what regions of the cerebellum?
Lateral cerebellar hemispheres
How many lobe does the cerebellum have?
3
What are the names of the cerebellar lobes?
Anterior Lobe
Posterior Lobe
Flocculonodular lobe
Name the Cerebellar Penduncles?
Superior peduncles
Middle peduncles
Inferior peduncle
Describe the Superior Peduncles.
-Primary efferent:
-projects to motor nuclei in thalamus to relay signal to UMN and pre motor cortex (CST/CBT)
-Direct projections to red nucleus (rubrospinal tracts) and superior colliculus
Afferent singles are recieves from spinocerebellar tract
Describe the Middle Penducles.
-Afferent input
-input from contralateral pontine nuclei
- Then the pontine nuclei integrates info from cerebral cortex and superior colliculus Afferent singles
Describe the middle penduncles.
-Afferent input
-input from contralateral pontine nuclei
- Then the pontine nuclei integrates info from cerebral cortex and superior colliculus
Describe the inferior peduncles.
-Contains both Afferent and efferent signals
-Afferent from vestibular nuclei, spinal cord, and brainstem tegmentum (inferior olivary N.)
-Efferent project to vestibular nuclei and reticular formation (vestibulospinal and reticulospinal tracts)
Name the Deep cerebellar nuclei.
- Fastigial nuclei- vermis
- Globose nuclei and Globose —> form the interposed nuclei- intermediate zone
Don’t Eat Greasy Food
Name the functional unit of local neurons within the cerebellum.
-prukinje cell (inhibitory)
- Deep nuclear neuron (excitatory)
What are the three layers of the cerebellar cortex from outer most to inner most?
- Molecular layer
- Purkinje Cell layer
- Granular layer
The granular layer contains what type of nerve cells?
-Golgi cell
- Granule cell
Describe the nerve fibers responsible for input.
- mossy fibers
-Climbing fibers
What are Mossy fibers?
All regions of CNS
Axons from pontine nuclei to mossy fibers to granule cell
What are climbing fiber cells?
Connects to inferior olivary nucleus and synapses with deep cerebellar nuclear cell and purkinji cell.
What nerve cells are responsible for output in the cerebellum?
Purkinje cells and deep nuclei
Describe the Purkinje cells function.
Inhibit the cellular and vestibular nuclei
Describe the deep nuclei function.
Excitatory output from cerebellum to cortical region
