Lec 11: Urticaria and Angioedema

Question 1

True of urticaria and angioedema EXCEPT

A. wheal and flare reaction
B. initiated at the level of the small venules
C. due to vasodilation and increased vascular permeability
D. due to stimulation of type C unmyelinated afferent cutaneous neurons
E. NOTA

Answer 1

E. NOTA

Question 2

These cells are the most commonly involved in urticaria.

Answer 2

mast cells

Question 3

The following are characteristics of urticaria EXCEPT

A. fibrin deposition
B. vasopermeability
C. perivascular infiltration
D. leukocytoclasis
E. NOTA

Answer 3

D

There should be minimal endothelial swelling and no leukocytoclasis.

Question 4

These substances cause hives when injected into the skin EXCEPT

A. histamine
B. platelet activating factor
C. bradykinin
D. substance P
E. NOTA

Answer 4

E. NOTA

Question 5

True of urticaria EXCEPT

A. pruritic
B. central swelling
C. non-blanching
D. fleeting
E. NOTA

Answer 5

C

Urticaria should blanch with pressure.

Question 6

T/F

Frequently, there is central clearing in urticaria.

Answer 6

T

Question 7

True of angioedema EXCEPT

A. pitting edema 
B. skin is not hot
C. present on non-dependent areas
D. resolution is slower
E. NOTA

Answer 7

A

Angioedema is non-pitting edema and not similar to pre-tibial pitting edema.

Question 8

Up to how long can angioedema persist.

Answer 8

72 hours

Question 9

Differentiate urticaria and angioedema based on the location of manifestation.

Answer 9

urticaria - virtually any part of the body

angioedema - face, tongue, extremities, genitalia

Question 10

What are the two main classifications of urticaria?

Answer 10

spontaneous

inducible

Question 11

What is the cut-off time for you to say that the urticaria is chronic in nature?

Answer 11

6 weeks

Question 12

These are inducible urticarias EXCEPT

A. cold contact urticaria
B. dermographism
C. cholinergic urticaria
D. acute urticaria
E. NOTA

Answer 12

D

Acute urticaria is a type of spontaneous urticaria.

Question 13

Urticaria affects how many percent of the population?

Answer 13

15-20%

Question 14

True of acute urticaria EXCEPT

A. duration of few days to few weeks
B. incidence of 15-20% of population
C. etiology usually undetected
D. most are mild and never seen by physician
E. NOTA

Answer 14

C

Etiology of acute urticaria can usually be determined.

Question 15

Why are acute urticarias typically not seen by physicians?

Answer 15

It has probably resolved by the time they were seen by doctors.

Question 16

Enumerate four causes of acute urticaria.

Answer 16

viral infections
drugs
food
vaccines

Question 17

T/F

The etiology of chronic urticaria is rarely found.

Answer 17

T

Question 18

In what ages is chronic urticaria most commonly found.

Answer 18

common in the 3rd and 4th decade of life

Question 19

True of physical urticarias EXCEPT

A. reproducible by environmental factors
B. most frequent in children
C. episodic and often limited
D. usually unresponsive to corticosteroids
E. NOTA

Answer 19

B

Physical urticarias are more frequent in young adults.

Question 20

This is the most common cause of chronic urticaria.

Answer 20

non-physical / non-vasculitic stimuli