Lec 10

Question 0

two recombinant chromosomes

Answer 0

outer 2 same, middle different

Question 1

• calculated by using recombination frequencies
• meausred in map unites
• calcualte distnaces along chromosome, using number of base pairs

Answer 1

genetic maps

Question 2

two non recombinant

Answer 2

all same

Question 3

most numerous phenotype

Answer 3

nonrecombinant

Question 4

least numerous

Answer 4

double crossover

Question 5

Lod scores

Answer 5

estimates gene distance

Question 6

genetic markers

Answer 6

easy to identifiy

Question 7

loss of both members of a pair of homologus chromosomes

Answer 7

nullisomy

Question 8

loss of a single chromosome

Answer 8

monosomy 2n-1

Question 9

gain single choromosme

Answer 9

trisomy 2n+1

Question 10

change in number of individual chromosomes

Answer 10

anueploidy

Question 11

tetra

Answer 11

2n+2

Question 12

double trisomy

Answer 12

2n+2

Question 13

double monomy

Answer 13

2n-1-1

Question 14

double terasomy

Answer 14

2n+2+2

Question 15

X inactivation is an example of what?

Answer 15

dosage compensaiton

Question 16

down syndrom

Answer 16

trisomy 21

Question 17

familal down syndrom

Answer 17

45 chromosomes part of 21 goes elsewhere example of robertsonian translocation

Question 18

nail

Answer 18

autosomeal dominant trait.. LMX1B

Question 19

Trisomy 10 Edward Syndrom

Answer 19

mental retardation
deaht in year
low set of ears, deformed feet

Question 20

trisomy 13

Answer 20

patau
mr
cleft lip extra fingers big forhead death

Question 21

trisomy 8

Answer 21

normal life

mr

Question 22

chromosems inherted from same parent

Answer 22

uniparental disomy
cystic fibrosis
prader willi

Question 23

nondisjuction in mitosis region o ftissue is different

Answer 23

turners

mosaicism

Question 24

number of sets of chromosmes is different more common in plants

Answer 24

polyploidy

Question 25

extra sets of chromosomes from 2 or MORE species

Answer 25

allopolyploidy

Question 26

extra sets of choromosomes from species

Answer 26

autopolyploidy

Question 27

paracenric

Answer 27

do NOT include chromosome

Question 28

pericentric

Answer 28

DO include chromosome

Question 29

may break gene forme inverstion loop

Answer 29

inversion

Question 30

crossing over of inversion causese

Answer 30

normal non recom 2 non viable one non para

Question 31

a specific set of linked genes non random association btw alles linkage disequilbirum

Answer 31

haplotype

Question 32

method used for postiiioning gnes on chromosomes -mutation will form cell line cancer tumor

Answer 32

somatic cell hybridizaiton

Question 33

Jimison weed

Answer 33

12 trisomimc mutaions each for different pair of choromosmes does nOT effect nuclotie abnormal gene dosage

Question 34

ajacent 1 and 2 segregation

Answer 34

non viable gametes

Question 35

alternate seg

Answer 35

viable gametes

Question 36

seg translocation

Answer 36

large amount of genes are moved

Question 37

translocation

Answer 37

movement of genetic material btw non homologous chromosomes

Question 38

reciprical translocaiton

Answer 38

movement bt nonhomologous chormoosmes | more common than non

Question 39

nonreciprical

Answer 39

momemnt from one to another without exchagne

Question 40

cri du chat snydrom

Answer 40

deletion of shrot arm of chrom 5... child is heterozygous fro deletion results in small head, wide eyes, round face, mR, distinct cry

Question 41

wolf hirschhorn

Answer 41

``` dletion of short arm of 4, small head high forehead wide nose cleft lip and palate sever MR ```

Question 42

Tandem duplication

Answer 42

duplication region is immediatley adjacent

Question 43

displaced duplicaiton

Answer 43

located some displacement from duplicaiton

Question 44

reverse duplication

Answer 44

inversted

Question 45

Inhertiance pattern of bar mutions

Answer 45

unequal cross over, bc they are not well lined up

Question 46

deletion effects

Answer 46

imbalance of gene product, expression of normally recessive gene duplicaiton may cause evolution... could be bad

Question 47

psudodomminat

Answer 47

is recessive but bc of deletion appear domoninat bc both parents do not have gene

Question 48

haplosuficiency

Answer 48

single copy not sufficent to create wild type

Question 49

band rich in A-T base pairs

Answer 49

G band

Question 50

difference in amoounts of CG and AT

Answer 50

Q band

Question 51

centromeric heterochromati

Answer 51

C bnad

Question 52

R band

Answer 52

rich in CG

Question 53

autoploidy

Answer 53

3n

Question 54

of observed double cross over =

Answer 54

coefficentX nubmer of expected

Question 55

coefficent of coincendince

Answer 55

of observed double crossovers/ number of expected double crossoovers

Question 56

inference =

Answer 56

1- coefficent

Question 57

expected number od couclbe crossover

Answer 57

gene one cross overX gene one cross overX total number