Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Rs Micro > Lec 1 > Flashcards

Lec 1 Flashcards

1
Q

What’re the defense mechanism in RS system ⁉️

A 
🔺mechanical 
☀︎︎coughing 
☀︎︎glottal reflex 
🔺structural 
Mucous 
Ciliated epithelium 
🔺fluid 
Iga ➡️upper tract 
IgG ➡️lower 
🔺cellular 
Alviolar macrophages ➡️lower
Neutrophils ➡️with information
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What’s the symptoms that’s shared by all of the viral respiratory tract infections ⁉️

A 
🔹chills 🥶
🔹fatigue 😩
🔹vomiting 
🔹diarrhea 
🔹pneumonia 
🔹rs faliuer 
🔹conjunctivitis 👁
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What’s influenza virus 🦠⁉️

A

It’s an acute febrile 🔥illness with variable systematic symptoms varies from fatigue to rs failure and death ☠️

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What’re the main genera groups of influenza ⁉️

A

🔸influenza A
🔸influenza B
🔸influenza C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What’re the main structure for orthomyxovirus ⁉️

A

🔺RNA envelope ✉️
🔺has an RNA polymerase ➡️enzyme helps in infectivity 🙂
🔺has transportation error
🔺single stranded RNA with negative sense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What’s the number of RNA segments in each orthmyxovirues type

A

🔹influenza A➡️8
🔹influenza B ➡️8
🔹influenza c➡️7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What’s the main structure in the orthomyxovirues⁉️

A

🔺hemagglutinin➡️against AB
🔺ribonucleoprotein➡️main group classification
🔺nuraaminidase➡️subtype classification
🔺no structural proteins and ion channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The classification of influenza virus 🦠 depends on ⁉️

A

▪️ribonucleprotine ➡️main type

▪️nuraaminidais ➡️subtype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What’s the main function of hemagglutinin ⁉️

A

🔺17subtype
🔺it’s a structe in orthomyxovirues allowes the virus 🦠 to penetrate the endothelial cell in the RS tract by binding to sialic acid
🔺main determination to immunity (stimulate neutralizing antibodies production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mention a structure of orthomyxovirues that’s not found in type c ⁉️

A

Nuraminidase🌚

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Main features of nueraminidase⁉️⁉️

A

🔸not in type c
🔸determination of disease severity
🔸allows the release of the newly formed virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What’s the function of riboneucloprotein❓❓❓

A

🔺determined the main virus type

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mention a structure that found only in type A influenza 🌚🌚

A

M protein ➡️
🔺found between capsid and envelopes
🔺act as an ion channel ➡️to change endosomal ph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

There are 2 types of antigen in influenza virus ⁉️

A

🔸group specific antigen ➡️A BC

🔸type specific antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What’s the structure that determine the antigen group specific ⁉️

A

🔺riboneuclprotien

🔺A B C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What’s the structure that determine the antigen specific type ❓❓

A

🔹hemagglutinin,,nuraminidase
🔹HA antibody ➡️provided protection
🔹NA antibodies ➡️don’t provide

17
Q

Antigenic changes are common in type what of orthomyxovirues ⁉️

A

AAA 👍🏼👍🏼👍🏼

18
Q

What’s the antigenic shift ❓

A

🔸only in type A
🔸major changes in the RNA genomics 🧬➡️that will lead to new hemagglutinin and neuraminidase
🔸pre existing AB will not protect
🔸it will lead to pandemic 😷

19
Q

When the antigen shift happened 🔺

A

When two varieties affects the same cell

20
Q

Mention 2 things that special in type A influenza ⁉️⁉️

A

🔹there’s m protein ➡️responsible for endosomal ph ,,,act as an ion channel
🔹there’s antigen shift ➡️major changes in rna lead to make new HA and NA and pandemic

21
Q

What’s the anteginc drift ⁉️

A

🔹happened in all types
🔹epidemic
🔹minor changes ➡️mutations in HA and NA
🔹partially protection

22
Q

What’s the host of each orthomyxovirues type 🧬🙂❓

A

A➡️many hosts (antigen shifts )
B ➡️human
C➡️no NA (human and 🐷)

23
Q

What’s the nomenclature of orthomyxovirues ⁉️

A 
🔺type 
🔺place of isolation 
🔺number of strain 
🔺year of isolation 
🔺subtype 
➡️if it’s not isolated from humans we should mention the source
24
Q

What’s viremia ⁉️

A

The presence of virus 🦠 in blood 🩸

25
Q

Orthomyxovirues pathogenesis factors ⁉️

A

🔹host factors ➡️immunity,congenital abnormalities
🔹environmental factors ➡️crowdness,season
🔹viral factors ➡️amount and size

26
Q

What’s the pathogenesis mechanism of orthomyxovirues ⁉️

طريقة سير المرض في الجسم 🌚👍🏼

A

🦠structural and functional damage for RS cell
🦠direct tissue toxicity
🦠increase the chance to have bacterial infection 🧫

27
Q

Mode of orthomyxovirues transmission 😷

A

Respiratory droplets 💧 🙂

28
Q

Incubation period of orthomyxovirues ❓

A

1-4 days

29
Q

Symptomatic period of orthomyxovirues ❓

A

3-7

30
Q

When the orthomyxovirues is considered to be severe ☠️⁉️

A

🔺lung and heart chronic disease
🔺immunocompramise
🔺Old people

31
Q

What’s the pulmonary complications of orthomyxovirues ⁉️

A

🧫 bacterial infection
🦠primary influenza pneumonia
🦠croup الخناق ➡️in child 👶🏻

32
Q

Non pulmonary complications of influenza ⁉️

A

Cardic➡️myositis (rare in type b)👶🏻👶🏻
Liver➡️reyes syndrome
Cns➡️guillian syndrome (autoimmune disease

33
Q

The least influenza pandemic 😷⁉️

A

2009➡️type A

34
Q

Orthomyxovirues diagnosis ⁉️

A

🔹pcr
🔹culturing
🔹serology
🔹immunofluresant detection

35
Q

People who should take the vaccine 💉

A

➡️people with chronic lung 🫁 and heart disease
➡️old people
➡️immunocompramised
➡️pregnant women

36
Q

What’s the aim of vaccine 💉

A

▪️to make hemagglutinin antibody

▪️2 A variant type and 1-2 b type

37
Q

Major vaccine types

A

🦠sub unit vaccine ➡️👶🏻
Life attenuated
Inactivated

Rs Micro (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions