Learning objectives from tutorials Flashcards

1
Q

Meanings of the term depression

A

Symptom - an emotion within the range of normal experience
Syndrome - a constellation of symptoms and signs
Illness - “recurrent depressive disorder”

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2
Q

Describe the symptoms of depressive syndrome

A

Low mood
Anhedonia - complete inability to feel pleasure
Low energy

Poor appetite 
Poor sleep 
Poor concentration
Reduced libido 
Tearfulness 
Negative thoughts 
Suicidal thoughts

May have psychotic symptoms

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3
Q

Describe the features of depressive syndrome which may be seen on a mental state examination

A

Appearance - poor self care, reduced facial movement
Behaviour - psychomotor retardation or agitation
Mood - subjective and objectively depressed, reduced range and intensity of affects
Speech - slow, quiet, monotonous
Thought form - thoughts may be slowed
Thought content - negative, guilty or suicidal; depressive delusions if psychotic
Abnormal perceptions - possible auditory hallucinations if psychotic; reduced eye contact
Insight - usually present
Cognition - not usually impaired

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4
Q

Describe the complications of depression

A

Suicide
Psychosis
Social and occupational dysfunction - unemployment or problems at work, family and relationship problems, social isolation

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5
Q

What is the minimum length of time antidepressants should be continued after eliciting a response

A

6 months

Should be continued for 6-12 months; can be continued long term if chronic depression, or as prophylaxis where depressive episodes have been frequent or severe, psychotic or involved in a single suicide attempt

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6
Q

Give an example of a biological treatment for depression

A

Antidepressants

SSRI
MOA
TCA

Electro-convulsive therapy

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7
Q

Give a psychological treatment for depression

A

Cognitive behavioural therapy

Interpersonal psychotherapy

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8
Q

Give a social treatment for depression

A

No specific treatments but modification of lifestyle factors may be helpful

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9
Q

Describe the symptoms of a manic episode

A

Abnormally elevated or irritable mood associated with increased energy and activity, increased talkativeness, inflated self esteem, decreased need for sleep, increased libido, overspending, reckless behaviour, racing thoughts IN A SYNDROMAL PATTERN

May include psychotic symptoms

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10
Q

Describe features seen in mania with psychotic symptoms

A

Speech can show flight of ideas - thoughts jumping from topic to topic
Delusions - usually grandiose
Hallucinations - usually second person auditory

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11
Q

Define the criteria for bipolar affective disorder

A

Repeated episodes of mania and depression

At least 2 episodes of mania or one episode of mania and one episode of depression

Those who only have mania are rare but are classed as having bi-polar

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12
Q

The basic treatment modality for acute mania

A

Benzodiazepines/sedation - to calm patient down and re-instate normal sleep pattern

Antipsychotics - have sedative and mood-stabilising properties, as well as reducing any psychotic symptoms

Consider stopping any Antidepressants as these can worsen or induce mania but may be appropriate if have worked in the past

Mood stabilisers - lithium, anticonvulsants

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13
Q

Basic treatment modalities used in adolescent psychiatry

A

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14
Q

Issues of consent in the assessment and treatment of young people

A

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15
Q

Clinical features OD anorexia nervosa

A

1) primary psychological disturbance - patient has dread of being overweight and imposes a new target weight - often associated with disturbance of perception
2) patient restricts food intake and uses other methods to reduce weight (self-induced vomiting, diuretics, laxatives, xs exercise)
3) BMI

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16
Q

Clinical features of bulimia nervosa

A

Episodes of binge eating - feeling of loss of control

General pre-occupation with eating

Attempts to compensate for weight gain by restricting food intake between binges (self induced vomiting, diuretics, laxatives appetite suppressants, or xs exercise

A fear of being overweight

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17
Q

Associated features and complications of eating disorders

A

Lanugo hair - fine, downy hair seen in malnourished
Russel’s sign - calluses on knuckles or back of hands due to repeated self induced vomiting
Erosion of tooth enamel
Loss of secondary sexual characteristics
Vitamin deficiency states, peripheral neuropathy
Electrolyte imbalances - due to malnutrition or vomiting
Hypotension, bradycardia
Suicide and self harm are more common
Death is due to complications - malnutrition, electrolyte distubrance, ruptured oesophagus or cardiac failure

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18
Q

Management of eating disorders

A

Dietary support and re-feeding if dangerously low weight

CBT orientated therapy with dieticians

Family therapy/intervention with the family

SSRI can help with bulimia but there isn’t an evidence basis for their use in adolescents and they are not useful in anorexia

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19
Q

Describe key aspects of assessment and management after attempted suicide

A

Assessment by a special trained staff member with ready access to psychiatric opinion

Identify any psychiatric disorder and offer referral to local mental health services for treatment

Consider the need for in-patient psychiatric care

Involvement of other relevant agencies - social services, family, school

Develop a safety plan - practical measures such as removing means to attempt suicide again (by locking medicines away) and identify person they can contact if they feel suicidal again

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20
Q

Mental state examination components

A

Appearance and behaviour

Mood - subjective, objective, affect

Speech

Thought form 
Thought content (delusions, suicidal intent)

Abnormal perceptions

Insight

Cognition

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21
Q

Differential diagnosis for presentations of disturbed or antisocial behaviour

A

Conduct disorder
Oppositional defiant disorder
ADHD
Depression

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22
Q

Basic management of common psychiatric conditions presenting with disturbed behaviour

A
Family education
Parent management training
Family therapy 
Educational support 
Anger management for the child 
Treat comorbid problems, e.g. ADHD
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23
Q

Mental health disposals available to the court

A
Assessment order 
Treatment order 
Committal to hospital 
Interim compulsion order 
Restriction order (can only be used with compulsion order and when there is significant risk to the public)
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24
Q

What are the possible civil provisions

A

Emergency detention certificate

Short term detention certificate

Compulsory treatment order

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25
Q

Emergency detention certificate

A

Any registered medical practitioner

Lasts for a maximum of 72 hours

Patient must be likely to have a mental disorder

Patients decision making ability is significantly impaired

Significant risk to health, safety or welfare, or to safety of others

No alternative to treatment in hospital and required urgently

Short term detention impractical

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26
Q

Short term detention certificate

A

Applied by approved medical practitioner (AMP) with mental health officer (MHO) consent

Patient has mental disorder

Patients ability to make decisions about the provision of medical treatment is significantly impaired as a result of that mental disorder

It is necessary to detain the patient in hospital for the purpose of determining what medical treatment should be given to the patient or to give them medical treatment

Significant risk to health, safety and welfare of patient or others

Lasts 28 days from day admitted to hospital

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27
Q

Compulsory treatment order

A

Granted by mental health tribunal and lasts up to 6 months

Must have mental disorder

Medical treatment available to prevent mental disorder worsening or to alleviate effects

Significant risk to health, safety or welfare, or to safety of others

Significant impairment in decision making ability

Treatment cannot be provided informally

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28
Q

Describe the features of chronic alcohol misuse which may be seen on a mental state exam

A
Appearance 
Behaviour 
Mood - subjective, objective, affect
Perception 
Insight
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29
Q

Screening tools regarding alcohol

A

FAST (how often had >X drinks on one occasion, how often forget things, how often have failed what expected of you, has anyone ever been concerned) score 3+ = hazardous level

CAGE (have you ever felt you should CUT down, have people ANNOYED you by criticising your drinking, have you ever felt GUILTY about your drinking, have you ever had a drink first thing in the morning (EYE OPENER) 4 = alcoholism

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30
Q

Define delusion

A

A fixed belief, held despite rational argument or evidence to the contrary

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31
Q

What is a grandiose delusion

A

Exaggerated beliefs of being special or important (e.g. Rich and famous)

32
Q

What are persecutory (or paranoid) delusions

A

Beliefs that others are trying to persecute or cause harm (e.g. People are spying on the patient)

33
Q

What are nihilistic delusions

A

Beliefs regarding the absence of something vitally important (e.g. The patient is dead, homeless, or their organs are rotting)

34
Q

What are delusions of reference

A

Beliefs that ordinary objects, events or other people’s actions have a special meaning or significance for the patient
- e.g. News reports relate to them, objects are arranged as ‘signs’

35
Q

What are delusions of control

A

Beliefs that outside forces control the patient in some way

- this includes delusions of passivity or thought interference

36
Q

What are delusions of thought interference

A

Withdrawal: belief that someone or something is removing thoughts from the patient’s head

Insertion: Belief that thoughts have been put into patient’s mind so they are thinking someone else’s thoughts

Thought insertion: the belief that thoughts are broadcast to others

37
Q

What is a hallucination

A

Perception in the absence of a stimulus - hearing a voice when no-one has spoken (they feel the same as any other perception)

Could be auditory, visual, touch (tactile or deep sensation), olfactory, gustatory

38
Q

Common auditory hallucination in schizophrenia

A

Voices in the 3rd person - discussing or arguing with the patient

39
Q

Medical causes for depression

A

Thyroid disorder - hypothyroid
Chronic pain
Medications such as beta blockers
Alcohol or drug use

40
Q

Describe demographic and historical factors which can increase the risk of subsequent suicide

A
Older age 
Male gender 
Mental illness 
Co-morbid physical illness 
Chronic pain 
Use of drugs or alcohol 
Social isolation - bereavement, disconnection from support systems e.g. School, family, work through unemployment or retirement 
Previous suicidal behaviour 
High lethality of method used and ongoing availability of method 
Physical and sexual abuse
41
Q

How would you conduct a history with someone who has attempted suicide

A

Description of the act - violent means? Did they think it would kill them (Perceived lethality)? Planned in advance? Were they likely to be discovered? Alcohol or illicit drugs involved (increases chance of death but person less likely to have intended to die), was there a precipitant?

Circumstances - prior: social difficulties, psychiatric illness. And now: how do they feel about it, do they regret it, do they still feel suicidal, have circumstances improved since the attempt

Current plans

42
Q

Describe the acute and chronic symptoms of schizophrenia

A

In the acute stage - hallucinations or delusions relating to disruption of ego-boundary

In the chronic stage - deficits of affect, motivation and thinking

43
Q

What are the first rank symptoms of schizophrenia

A

A = auditory hallucinations - hearing thoughts being repeated aloud, 3rd person auditory hallucinations

B= broadcasting of thought - thought withdrawal, thought insertion, thought broadcasting

C= controlled thought (delusions of control) : Passivity phenomena - delusions that their thoughts, feelings or impulses are driven by some external force or person; Somatic passivity - a delusion that some external force is causing physical sensations (which may be hallucinations) in their body

D = Delusional perception - a delusion which arises because of a completely unrelated happening in external reality

44
Q

Non-psychotic symptoms of acute schizophrenia

A

Mood disturbance and unusual behaviour

45
Q

Negative symptoms of schizophrenia

A
Apathy and lack of motivation
Poverty of speech (and lack or thoughts)
Blunted or incongruous affect (and lack of emotions) 
Social withdrawal
Occupational decline
46
Q

Cognitive symptoms of schizophrenia

A

Poor executive function (reduced decision making ability) and poor abstract reasoning

47
Q

Differential diagnosis in a psychotic patient

A

Psychotic mania or depression
Delirium
Drug induced psychosis or intoxication
Medications - steroids
Cerebral causes - tumour, infection, infarction, epilepsy
Endocrine disease - thyroid, chronic hypoglycaemia, cushing’s, addisons
Systemic illness such as anaemia, carcinoma or sarcoid

48
Q

Treatment of schizophrenia in the acute stage

A

Antipsychotic meds

Sedatives

49
Q

Treatment of schizophrenia in the long term

A

Antipsychotic medication

Support in the community

Rehabilitation in dedicated facilities

**psychological therapies are not useful

50
Q

What percentage of those with acute schizophrenia kill themselves

A

10%

51
Q

Dependence syndrome

A

3 or more of the following features which occur together for at least 1 month or repeatedly over a 12 month period

Compulsion - strong desire to take
Difficulties controlling use
Continued use despite harmful consequences
Salience - higher priority given to a substance use than to other activities and obligations
Increased tolerance
Withdrawals when substance is used/stopped

52
Q

Tolerance

A

A drugs early effects are later achievable only by higher doses

53
Q

Withdrawal state

A

A group of symptoms of variable severity occurring on absolute or relative withdrawal of a psychoactive substance, after persistent use of that substance

54
Q

Physical complications of alcohol misuse

A

Accidental injury, violence, sexual dysfunction

GI - liver disease, gastritis, peptic ulcer, GI bleeding, pancreatitis

Cardiovascular - HT, heart disease, stroke

Cancer - mouth, oesophagus, liver

Neurological - fits, confusional states, head injury, Wernicke’s or Korsakoffs)

55
Q

Psychiatric complications of alcohol misuse

A
Deliberate self harm 
Anxiety states 
Depression 
Morbid jealousy 
Alcoholic hallucinosis
56
Q

Social complications of alcohol misuse

A

Employment and financial difficulties

Marital and family problems

Criminal convictions

57
Q

Treatment of alcohol misuse

A

Alcohol counselling and psychological input
Referral for help with social/occupational issues
Encourage use of community support - AA
Thiamine - to prevent Wernicke’s/Korsakoffs
Detoxification if appropriate - benzodiazepines
In patient or residential treatment
Medication to help with abstinence

58
Q

Medication to help with abstinence

A

Acamprosate or naltrexone for alcohol craving

Disulfram (antabuse) makes you feel sick if you drink alcohol

59
Q

Treatment of opiate dependence

A

Counselling and psychological input
Referral for help with social/occupational issues
Encourage use of community supports
In patient or residential treatment
Methadone - gradual reduction or harm reduction by staying on same dose

60
Q

Which antipsychotic has been shown to cause no tardive dyskinesia

A

Clozapine

61
Q

Atypical antipsychotics include

A

Olanzipine
Risperidone
Clozapine

62
Q

Typical antipsychotics include

A

Chlorpromazine

Haloperidol

63
Q

When is clozapine indicated

A

For those who don’t respond to other antipsychotic medications or are intolerant to them –> i.e. Treatment resistant schizophrenic patients

64
Q

Potential side effects of clozapine include

A
Neutropenia
Seizures
Idiopathic hyperthermia 
Weight gain 
Hypersalivation
65
Q

Conditions that could be caused by using antipsychotics

A

Obesity and weight gain
Diabetes
Metabolic syndrome

66
Q

What is metabolic syndrome

A

Obesity
Hypertension
Dyslipidaemia
Abnormal glucose metabolism

67
Q

Which drugs are most problematic associated with obesity, diabetes and metabolic syndrome

A

Clozapine and olanzapine

68
Q

Diagnosis of metabolic syndrome

A

BP>130/85
Serum HDL cholesterol >1.04 Male or >1.29 Female
Serum triglyceride >1.69
Fasting glucose >6.1
Waist circumference >102cm male or >88cm female

69
Q

Which drugs are prone to causing hyperprolactinaemia

A

Many antipsychotics, especially amisulpride, risperidone, and typical antipsychotics

70
Q

Effects of hyperprolactinaemia

A
Galactorrhoea 
Menstrual irregularity 
Sexual dysfunction 
Osteoporosis
Increased risk of breast cancer 
Serum prolactin levels should be checked if patients report any symptoms
71
Q

Cardiac effects of antipsychotics

A

QT elongation

Which can lead to potentially fatal tachyarrhythmias

72
Q

Differential diagnosis of autism

A
Deafness
Asperger's 
Specific language disorder 
Learning disability
Child hood schizophrenia or Rett's syndrome 
Neglect
73
Q

What is Wernicke’s

A

Acute thiamine deficiency

Triag of confusion, ataxia and opthalmoplegia

74
Q

What is korsakoff’s

A

Irreversible anterograde amnesia - can register new events but can’t recall within a few minutes

75
Q

Why get extrapyramidal side effects

A

Widespread dopamine blockade