Learning and Memory Flashcards
Explain classical conditioning
A conditioned stimulus (CS) is presented which elicits no response. An unconditioned stimulus (UCS) is then presented which automatically elicits an unconditioned response (UCR). The CS is paired with the UCS a number of times and so the learned response is called the conditioned response (CR). Pavlov’s dog is the most known example of classical conditioning.
Explain instrumental conditioning
Also known as operant conditioning where a response leads to a reinforcer (increases future probability of response) or a punishment (decreases the future probability of response).
What are the traditional two categories of learning?
Classical and Instrumental (operant) conditioning.
What are the two principles Lashley proposed about the nervous system?
- equipotentiality—all parts or the cortex contribute equally to complex behaviours
- mass action - the cortex works as a whole and thereofre more cortex is better
What is an engram?
the physical representation of what has been
learned
What is the physiological explanation of a ‘flashbulb moment’? aka a highly emotional experience.
highly emotional experiences arouse the locus
coeruleus, which increases norepinephrine release throughout the cortex and dopamine release in the hippocampus. They also increase the secretion of epinephrine and cortisol that activate the amygdala and hippocampus.
How does the cortex store a working memory during a delay?
Occasional bursts of gamma oscillations (45 to 100 Hz) occur in cells that responded to a stimulus, but the bursts alternate among cells instead of persisting throughout the delay in any one cell.
What is Korsakoff’s Syndrome?
Brain damage caused by prolonged thiamine deficiency. This is needed to metabolize glucose. This is common among peple with sever alcoholism. Some symptoms include apathy, confusion, memory loss and confabulation.
Which chromosome is linked to most cases of early-onset alzhiemers?
Chromosome 21 (the same that is duplicated in those with Down Syndrome)
What is the name of the protien which is associated with alzhiemers and what does it do?
Amyloid-β - this accumulates inside and outside neurons and spread from cell to cell. It damages axons and dendrites, decreases synaptic input, and decreases plasticity.
What are plaques and tangles?
Damaged axons and dendrites (from amyloid-B) cluster into structures called plaques that damage the cerebral cortex, hippocampus, and other areas.
Tangles are structures formed from degeneration within neurons caused by tau protien.
Both are found within the cortex of those with alzheimers.
What is the most plausible explanation for infant amnesia?
The rapid learning in early childhood displaces memories formed in infancy.
What is anterograde amnesia?
Inability to form memories after an injury/damage
What is retrograde amnesia?
Inability to recall memory for events prior to injury/damage
What are episodic memories?
Memories of personal events