LEA - Embryology Flashcards
at what week does the limb bud appear?
week 4
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during which week of gestation do the limb buds flatten?
week 5
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at what week do the lower limb buds undergo their first rotation?
week 6;
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- in this first rotation, the limbs move horizontally from the CORONAL to the SAGITTAL plane with the soles of the feet facing each other;*
- This is the first of two lower limb bud rotations. The second occurs in the following weeks*
during which week of gestation do the lower limbs undergo their second rotation?
week 7-8
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- the limb buds internally rotate 90 degrees during this time so that the knees and extensor compartment of the leg face anteriorly,*
- (in contrast, the upper limbs externally rotate 90 degrees)*
what is meant by “pre-axial” and “post-axial”?
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pre-axial:
- developmentally ventral muscles or the anterior condensation of mesoderm
- innervated by anterior divisions of ventral rami
-
post-axial:
- developmentally dorsal muscles or the posterior condensation of mesoderm
- innervated by posterior divisions of ventral rami
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what two embryological tissues make up the limbs?
what do they each give rise to?
mesoderm & ectoderm
- mesoderm gives rise to bones, ligaments, tendons, and dermis.*
- ectoderm gives rise to nerves, epidermis, nails, hair, and apical ectodermal ridge (AER)*
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failure of apoptosis between toe rays during limb bud development leads to what congenital condition?
syndactyly
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by week 8 of gestation, the foot is in what position?
plantarflexed & adducted
(or the equinus-supinated position)
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all bones of the lower limb form from ________ precursors
cartilaginous,
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- the process is known as endochondral ossification.*
- All bones originate from mesenchyme. However, flat bones of the skull skip the cartilaginous step and become osseous (intramembranous ossification).*
- All lower extremity bones form by endochondral ossification.*
what are the developmentally ventral muscle compartments of the hip and thigh?
posterior & medial muscle compartments.
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- (hamstrings & aDductors)*
- Remember: Ve**ntral = Pr**e-axial*
what are the developmentally dorsal muscle compartments of the hip and thigh?
anterior & lateral muscle compartments
(quadriceps & aBductors)
Remember: D_orsal = Po_st-axial
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what are the developmentally ventral muscle compartments of the leg and foot?
posterior (superficial and deep) muscle compartments of the leg,
and plantar intrinsic muscles of the foot
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what are the developmentally dorsal muscle compartments of the leg and foot?
anterior & lateral muscle compartments of the leg,
and dorsal intrinsic muscles of the foot
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Pre-axial muscles are innervated by which divisions of ventral rami?
anterior divisions innervate developmentally ventral (pre-axial) muscles
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post-axial muscles are innervated by which divisions of the ventral rami?
posterior divisions innervate developmentally dorsal (post-axial) muscles
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hip and thigh muscles that are developmentally ventral arise from what two skeletal landmarks?
ischium & pubis
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name the anterior divisions of the lumbar and sacral plexuses
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hip and thigh muscles that are developmentally dorsal arise from what two skeletal landmarks?
vertebral column & ilium
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name the posterior divisions of the lumbar and sacral plexuses
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what muscles, due to their innervations, have both developmentally ventral and dorsal compartments?
- biceps femoris: long head (tibial n.); short head (common peroneal n.)
- pectineus: femoral n. and obturator n.*
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*innervation is variable
a club foot deformity, seen in about 1/1000 births, is characterized by a foot in what position related to the three cardinal planes?
- Plantarflexed/equinus (sagittal plane)
- Adducted (transverse plane)
- Inverted/varus (frontal plane)
Known as “talipes equinovarus.” The term “talipes” is derived from “Talus” meaning “ankle”, and “pes” meaning “foot”. It makes sense that it’s a condition affecting the ankle and foot!
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