LDL GOALS

Question 1

What is the risk category for progressive ASCVD including unstable angina?

Answer 1

Extreme risk

Represents the highest level of risk for cardiovascular events.

Question 2

What defines the very high risk category in ASCVD?

Answer 2

Established clinical ASCVD plus diabetes or CKD ≥3 or HeFH

CKD stands for chronic kidney disease; HeFH stands for heterozygous familial hypercholesterolemia.

Question 3

What are the criteria for high risk in ASCVD?

Answer 3

• History of premature ASCVD (<55 years, male; <65 years, female)
• Established clinical ASCVD or recent hospitalization for ACS, carotid, or peripheral vascular disease, or 10-year risk >20%
• Diabetes with ≥1 risk factors
• CKD ≥3 with albuminuria
• HeFH

ACS refers to acute coronary syndrome.

Question 4

What defines moderate risk in the ASCVD risk categories?

Answer 4

≥2 risk factors and 10-year risk 10-20%

Risk factors may include diabetes, hypertension, and elevated cholesterol levels.

Question 5

What is the threshold for low risk in ASCVD?

Answer 5

• Diabetes or CKD ≥3 with no other risk factors
• <2 risk factors and 10-year risk <10%
• No risk factors

Low risk indicates a favorable cardiovascular risk profile.

Question 6

What is the LDL-C target for individuals at extreme risk according to ASCVD guidelines?

Answer 6

<55

LDL-C stands for low-density lipoprotein cholesterol.

Question 7

What is the LDL-C target for individuals classified as very high risk?

Answer 7

<70

Maintaining lower LDL-C levels is crucial for reducing cardiovascular risk.

Question 8

What is the LDL-C target for individuals at high risk?

Answer 8

<100

This target helps manage the overall risk of cardiovascular events.

Question 9

What is the LDL-C target for individuals at moderate risk?

Answer 9

<100

Similar to high risk, indicating a need for careful management.

Question 10

What is the LDL-C target for individuals at low risk?

Answer 10

<130

This target reflects a lower need for aggressive lipid-lowering therapy.

Question 11

What are the major risk factors for ASCVD?

Answer 11

• Advancing age
• Elevated non-HDL-C
• Elevated LDL-C
• Low HDL-C
• Diabetes
• Hypertension
• CKD
• Cigarette smoking
• Family history of ASCVD

Understanding these factors helps in risk assessment and management.

Question 12

صورة المصدر

Answer 12