Laxatives Flashcards

1
Q

Stool softener

A

Sodium docusate - particularly effective for faecal impaction

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2
Q

Bulking agent

A

Ispaghula husk - often first line but need adequate fluid intake, takes a few days to work

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3
Q

Stimulant

A
Senna
Bisacodyl
CI in obstruction, acute abdomen (cause unknown)
Can cause cramps
Excessive use can cause hypokalaemia
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4
Q

Osmotic

A

Macrogols e.g. laxido, movicol
CI in obstruction, ileus, perforation
Can cause bloating

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5
Q

Faecal impaction

A

1st line = macrogol AND/OR senna

2nd line = suppository

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6
Q

Opioid induced constipation

A

1st line = senna AND macrogol

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7
Q

Drugs which cause constipation

A
Opioids
Anticholinergics e.g. TCAs, SSRIs, antipsychotics, antihistamines
Iron salts
Calcium salts
CCBs esp. verapamil
Ondansetron
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