CP450 Flashcards
1
Q
Enzyme inducers
A
PC BRAS - phenytoin, carbamazepine, barbiturates, rifampicin, alcohol (chornic excess), sulphonylureas, St John’s Wort, topiramate
2
Q
Enzyme inhibitors
A
AO DEVICES - allopurinol, omeprazole, disulfiram, erythromycin, valproate, isoniazid, ciprofloxacin, ethanol (acute), sulphonamides
Other - grapefruit juice, amiodarone, SSRIs
Liver failure
3
Q
Contraception
A
Efficacy of progesterone-only preparations is reduced by enzyme inducers
Should switch to alternative form of contraception until at least 4 weeks after stopping the enzyme inducer
