Last Quiz Flashcards
1
Q
Pka SAR of Histamine
A
2
Q
Histamine Trans conformation favors?
Gauche?
A
- Trans- H1 and H2
- Gauche H3
3
Q
Synthesis of Histamine?
A
4
Q
Major metabolic pathways of histamine
What is special about the end product?
A
- It is recycle to DNA and RNA synthesis
5
Q
Histamine receptors
H1?
H2
A
- H1 inflammation
- H2 gastic acid secretion
6
Q
Inhibitors of Histamine release
Mast Cell Stabalizers some contain?
A
Chromone
7
Q
General structure of 1 generation Antihistamines
A
Sedation
8
Q
Examples of Enthylenediamines
h1 antagonists
A
9
Q
Ethanolamine ether antihistamines
A
Blocking aromatic hydroxylation, longer acting compared to diphenhydramine
Halogen
10
Q
Hydroxyzine is a ____ generation structurally similar to?
Its metabolite is?
A
- 1st generation
- Structurally similar to quitiapine
- Metabolite is 2nd generation cetirizine
- H1 antagonist
11
Q
A
