Last Patho Exam- HIV Flashcards
HIV
immune system impairment due to destruction of T cells and makes a patient more susceptible to infections and unusual cancers
HIV
immune system impairment due to destruction of T cells and makes a patient more susceptible to infections and unusual cancers
HIV is RNA or DNA based
RNA. HIV IS A RETROVIRUS
If you have HIV does it mean you have AIDS
NOPE!!
If you have AIDS does it mean you have HIV
YEP!!
HIV is transmitted by,..
sexual contact - semen or vaginal fluids during unprotected sexual contact
contact with infected blood- needles
infected mothers to newborns inutero
what is key in HIV transmission
PREVENTION!!!!!!!!!!!!!!
what is seroconversion
the point at which the person converts from negative HIV to positive tests (1-6 months after exposure)
Window Period
time after infection but before sreoconversion
HIV antibody test is negative but can transmit the virus
HIV must invade living host cell in order to replicate. TRUE OR FALSE
TRUE
CD4 antigen serves as..
receptor and allows HIV to invade cells
HIV enters T cells where…
viral RNA is transcribed to DNA using enzyme reverse transcriptase
what cell count drops and immune function is seriously impaired
CD4T
can HIV mutate
yup!
Stage 1
CD4 t-lymph count is >500. no aids defining condition Window period Test negative for antibodies viral load high but and very infectious fever, fatigue, rash for 1-2 weeks
Stage 2: Latent Period
CD4 t-lymp cound is 200-499
no aids defining conditions
symptoms occur but not those related to AIDS
Stage 3: AIDS phase
viral load tests measure plasma
HIV RNA levels
GI manifestations: opportunistic infections in HIV patients
Thrush and cytomegalovirus
both present with s/s of painful swallowing, retrosternal pain, inability to swallow and dehyration
HAART
highly active antiretrivrial therapy
Not a cure, but it is treatment for lie.
Goal is to sustain suppression of HIV replication resulting in undetectable viral load and increasing CD4 cell count to slow progression of AIDS
HIV is RNA or DNA based
RNA. HIV IS A RETROVIRUS
If you have HIV does it mean you have AIDS
NOPE!!
If you have AIDS does it mean you have HIV
YEP!!
HIV is transmitted by,..
sexual contact - semen or vaginal fluids during unprotected sexual contact
contact with infected blood- needles
infected mothers to newborns inutero
what is key in HIV transmission
PREVENTION!!!!!!!!!!!!!!
what is seroconversion
the point at which the person converts from negative HIV to positive tests (1-6 months after exposure)
Window Period
time after infection but before sreoconversion
HIV antibody test is negative but can transmit the virus
HIV must invade living host cell in order to replicate. TRUE OR FALSE
TRUE
CD4 antigen serves as..
receptor and allows HIV to invade cells
HIV enters T cells where…
viral RNA is transcribed to DNA using enzyme reverse transcriptase
what cell count drops and immune function is seriously impaired
CD4T
can HIV mutate
yup!
Stage 1
CD4 t-lymph count is greater than 500. no aids defining condition Window period Test negative for antibodies viral load high but and very infectious fever, fatigue, rash for 1-2 weeks
Stage 2: Latent Period
CD4 t-lymp cound is 200-499
no aids defining conditions
symptoms occur but not those related to AIDS
Stage 3: AIDS phase
less than 200 CD4 and t-lymph
remain stage 3 even if CD4 cells increase
without treatment HIV will progress to AIDS after 7-10 years
viral load tests measure plasma
HIV RNA levels
GI manifestations: opportunistic infections in HIV patients
Thrush and cytomegalovirus
both present with s/s of painful swallowing, retrosternal pain, inability to swallow and dehyration
HAART
highly active antiretrivrial therapy
Not a cure, but it is treatment for lie.
Goal is to sustain suppression of HIV replication resulting in undetectable viral load and increasing CD4 cell count to slow progression of AIDS
