Last Minute Stuff Flashcards
1
Q
Aliphatic hydroxylation
A
Ibuprofen, pentobarbital, cyclosporine
2
Q
Aromatic hydroxylation
A
phenytoin, propanolol, steroids
3
Q
N-Dealkylation
A
imipramine, diazepam, codeine, morphine, tamoxifen, caffeine
4
Q
N oxidation
A
chlorpheniamine, trimethylamine
5
Q
S oxidation
A
chlorpromzine, cimetidine
6
Q
1A2
A
acetaminophen
caffeine
theophylline
warfarin
7
Q
2A6
A
zidovudine, warfarin
8
Q
2C9
A
phenytoin
S-warfarin
hexobarbital
ibuprofen
9
Q
2C19
A
diazepam
omeprazole
propanolol
10
Q
2D6
A
amitriptyline
fluoxetine
timolol
codeine, hydrocodone
11
Q
2E1
A
acetaminophen
ethanol
12
Q
3A4
A
50%
13
Q
Hydrolysis (non p450)
A
aspirin
14
Q
Glucuronidation
A
acetaminophen, morphine, imipramine, cloxapine
UDP-Gluc transferases
15
Q
Sulfation
A
ethanol