last chapters Flashcards
virus
an infectious agent having a simple acellular organization with a protein coat and a nucleic acid genome, lacking independent metabolism, and multiplying only within living host cells (contain protein and nucleic acid; double-stranded or single-stranded).
Virion
a mature/complete virus particle; consists of a protein capsid surrounding a single nucleic acid molecule.
Viroid
an infectious agent that is a circular single-stranded RNA not associated with any protein; the RNA does not code for any proteins and is not translated; requires host cell DNA-dependent RNA polymerase. (only RNA; plant disease)
Prion
an infectious agent consisting only of protein; prions cause a variety of spongiform encephalopathies such as scrapie in sheep.
Satellite
subviral infectious agents composed of DNA or RNA encapsulated with the aid of an unrelated helper virus (either DNA or RNA).
Prophage
bacteriophage genome inserted and integrated into the circular bacterial DNA chromosome or existing as a plasmid.
Provirus
the genetic material of a virus as incorporated into, and able to replicate with, the genome of a host cell.
Retrovirus
a type of virus that converts single-stranded RNA into double-stranded DNA using reverse transcriptase (HIV).
Tropism
the selective infection of certain organisms or host tissues by a virus due to the presence of the specific receptor on the surface of tissues to which the virus binds.
Viral plaques
a clear area in a lawn of bacterial cells that results from their lysis by virus.
Plaque-forming Units (PFU)
determines the lowest concentration of virus that still infects cells; the unit of measure of a plaque assay. It usually represents a single infectious virion.
SARS-CoV-2 genome
severe acute respiratory syndrome coronavirus 2; RNA genome.
What is a receptor for SARS-CoV-2?
ACE2
cultivation of virus
Growth of viruses requires inoculation of appropriate living host.
Mutualism
type of symbiosis in which both partners gain from the association and are dependent on each other.