Language and Communication Flashcards

1
Q

What is aphasia, dysarthria, dysphonia, or mutism?

A
Aphasia = disorder of language
Dysarthria = slurred speech
Dysphonia = hoarseness
Mutism = no sounds can be utter even with muscle strength
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2
Q

What cortical region is Broca’s area? What cortical area is Wernicke’s area?

A

Broca’s area is the inferior frontal cortex. Wernicke’s area is the postero-superior temporal gyrus.

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3
Q

What area was posited (but later found not to be true) to cause conduction aphasia when lesioned? What is conduction aphasia?

A

Arcuate fasciculus. Conduction aphasia is when you can’t repeat.

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4
Q

Define lexical, semantic, and phonologic aspects of language, and where the apparatus for these likely resides in the brain?

A

Lexical (word recognition), semantic (word meaning) and phonologic (word formation) likely reside int he dominant superior temporal gyrus and surrounding areas

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5
Q

What does the inferior frontal gyrus participate in?

A

Production of words and phrases, grammar, syntax, and fluency

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6
Q

What other deficit typically accompanies Broca’s aphasia?

A

Since it is usually due to superior branch of middle cerebral artery lesion, they usually have contralateral facial and arm weakness as well.

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7
Q

What other deficit usually accompanies Wernicke’s or fluent aphasia?

A

Since it is usually due to a lesion in the inferior branch of the middle cerebral artery, typically have a contralateral superior quadrantanopsia

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8
Q

What usually accompanies global aphasia?

A

Due to lesion of the entire middle cerebral artery. Accomplished by contralateral hemiparesis, gaze preference, and contralateral hemianopsia

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9
Q

***What is prosody?

A

The rhythm, stress and intonation of speech. Presence of sarcasm, emphasis, contrast, focus etc.

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10
Q

***Lesion of what structure leads to dysprosody?

A

Lesion of the non-dominant perisylvian structures

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11
Q

What is the usual hemisphere of dominance for language?

A

Left hemisphere.

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12
Q

** What is the standard test for establishing language dominance?

A

Wada test, where a short acting barbiturate is injected into each hemisphere via carotid artery to see if it impairs language processes.

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13
Q

What are primary progressive aphasias?

A

Aphasias with insidious onset and slow progression, usually due to molecular abnormalities such as tauopathies in frontal and temporal lobes.

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14
Q

What features characterize Broca’s non-fluent aphasia?

A

Effortful, frustrated production which is limited, with grammatical and syntactical errors.

  • Repetition is absent.
  • Comprehension is spared.
  • Patients are frustrated by their errors
  • Patients have accompanying agraphia
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15
Q

What features characterize fluent aphasia?

A

Produce language fluently and effortlessly and is unaware that the production is flawed. Contains errors of sound or word substitutions (paraphasias)
-Repetition and comprehension poor

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16
Q

What is a transcortical motor aphasia?

A

A non-fluent aphasia but retains repetition, due to an extrasylvian motor aphasia. Usually due to white matter lesions in watershed areas between anterior and middle cerebral artery territories

17
Q

What is a transcortical sensory aphasia?

A

A fluent aphasia but retains repetition. Due to a lesion of extrasylvian sensory region in watershed areas between the middle and posterior cerebral artery territories

18
Q

What are the 3 subtypes of primary progressive aphasias?

A

Progressive non-fluent aphasia, semantic dementia (where speech is fluent but comprehension is impaired) and logopenic progressive aphasia (atypical of Alzheimer’s)

19
Q

What results when there are lesions of the non-dominant hemisphere for language?

A

Prosody, infection, tone, cadence, and other features of language that are not semantic but contribute to language’s meaning.

20
Q

What is a type of language therapy for aphasia?

A

Constraint induced therapy.

21
Q

What drugs may be helpful for aphasia?

A

Piracetam, memantine, donepezil, amantadine