Lange Q/A Flashcards

1
Q

What stage of sleep do sleep terrors occur?

A

Deep sleep. Stages 3&4

Sleep walking also occurs during stages 3/4

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2
Q

What stage of sleep do nightmares occur?

A

REM

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3
Q

Expressive language disorder

A

Markedly limited vocabulary
Making errors in tense
Having difficulty recalling words or producing sentences with developmentally appropriate length or complexity

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4
Q

Most effective treatment for bulimia nervosa

A

Cognitive-behavioral therapy

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5
Q

Most common method children use when attempting suicide

A

Substance ingestion

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6
Q

Side effects associated with Desmopressin

A

Headaches

Nausea

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7
Q

What is the percentage of comorbid child anxiety disorders and MDD?

A

50 %

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8
Q

Most common adverse effects of fluoxetine

A

Nausea (GI upset)
Insomnia
Agitation
Headaches

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9
Q

Rett disorder

A

Between 5 months and 48 months there is a deceleration of head growth, loss of hand skills with development of stereotyped hand movements such as hand wringing, loss of social interaction, appearance of poorly coordinated gait or trunk movements, severely impaired expressive and receptive language development with severe psychomotor retardation

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10
Q

Monozygotic twin concordance for Rett syndrome?

A

100 %

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11
Q

Following a diagnosis of Type I Diabetes, what percentage of children develop Adjustment Disorder?

A

33 %

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12
Q

First-line treatment for Tourette disorder

A

Clonidine

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13
Q

Most common comorbid disorder associated with Tourette’s?

A

Obsessive-compulsive disorder

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14
Q

Requirements for dx of Tourettes?

A

Both multiple motor tics and at least one vocal tic

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15
Q

Potential risk with taking stimulant

A

Tics

*Can exacerbate tics

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16
Q

What percent of children with learning disorders have a comorbid psychiatric disorder?

A

50 %

*Most commonly ADHD, anxiety, and depressive disorders

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17
Q

Likelihood that child with persistent enuresis will have a comorbid mental disorder

A

20 %

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18
Q

Common adverse effects of stimulants

A
Insomnia
Decreased appetite
Weight loss
Dysphoria
Irritability
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19
Q

Stimulants are effective in treating ADHD in what percent of people?

A

70 %

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20
Q

nonstimulant treatment of both child and adult ADHD

A

Atomoxetine

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21
Q

Common lab finding in anorexia nervosa

A

Hypercholesterolemia

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22
Q

This finding alone justifies inpatient admission for anorexia nervosa

A

cardiac arrhythmia

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23
Q

How old are children when the begin to understand the irreversibility of death?

A

7 to 8 years old

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24
Q

Frequent adverse effect of clonidine

A

Sedation

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25
Q

Identification

A

Process of adopting other people’s characteristics

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26
Q

Displacement

A

Defense mechanism in which emotions are shifted from one idea or object to another that resembles the original but evokes less distress.

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27
Q

Reaction formation

A

Defense mechanism. An unacceptable impulse is transformed into its opposite

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28
Q

Most common outcome of abuse

A

Major depressive disorder

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29
Q

Alexia

A

Inability to read

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30
Q

Agnosia

A

Inability to recognize objects despite intact senses

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31
Q

Anomia

A

Inability to name objects even though the object is recognizable and can be described by the patient

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32
Q

Nonpharm treatment for OCD

A

CBT

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33
Q

Chapped hands

A

Common in OCD due to extensive hand washing

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34
Q

MAOIs

A

Phenelzine
Isocarboxazid
Tranylcypromine

35
Q

Treatment for severe serotonin syndrome

A

Cyproheptadine

*5-HT2A antagonist

36
Q

Serotonin syndrome features

A

Mental status changes
Autonomic hyperactivity
Neuromuscular abnormalities

(tachycardia, flushing, fever, hypertension, ocular oscillations, myoclonic jerks)

37
Q

Atypical features of depression, such as weight gain, hypersomnia, mood reactivity, respond best to which drug?

A

Phenelzine (MAOI)

38
Q

Most patients who are going to have a response to antidepressants, do so in what time frame?

A

6 weeks

However, it can take 12 weeks to achieve a full response

39
Q

Benzos that are metabolized by only glucoronidation and can be given to patients with elevated LFTs

A

LOT
Lorazepam
Oxazepam
Temazepam

40
Q

Lithium level of 1.2

A

Nausea
Tremor
Diarrhea
Ataxia

41
Q

Lithium level of 1.5 to 2

A

seizures

42
Q

Lithium level of 2 or more

A

Acute renal failure

43
Q

Li level greater than 2.5

A

Coma/death

44
Q

If patient has akathisia and no other EPS, start what drug?

A

Propranolol

45
Q

Treatment of dystonia, parkinsonism

A

Benztropine

46
Q

First-line treatment options for Bipolar II

A

Lithium
Lamotrigine
Quetiapine

47
Q

Most common dangerous complication of NMS

A

Rhabdomyolysis

48
Q

Although there are no specific lab findings for NMS, what labs are often elevated

A

WBC

Creatine phosphokinase

49
Q

What long term side effect can occur if patient takes high dose Thioridazine.

A

Retinal pigmentation

*It may not remit with thioridazine is discontinued and can lead to blindness

50
Q

Labs that should be obtained before starting Lithium

A

Electrolytes
Creatinine
BUN
Thyroid studies (Li inhibits synthesis of thyroid hormone and its release from the thyroid)

51
Q

Don’t use this drug for pain in a person on Lithium

A

Ibuprofen
It can cause the Lithium level to become high
*Aspirin is safe

52
Q

2 most common side effects of methylphenidate

A

Difficulty falling asleep

Decreased appetite

53
Q

Antidepressant with risk of causing hypertension

A

Venlafaxine

54
Q

Medication that best improves the symptoms of tardive dyskinesia

A

Clozapine

55
Q

Risk of Sertraline during pregnancy

A

Persistent pulmonary hypertension of the newborn

56
Q

Treatment of bulimia nervosa

A

Fluoxetine,Topiramate, or psychotherapy

*meds are not generally helpful in anorexia

57
Q

Symptomrs of SSRI discontinuation syndrom

A

May occur 1 to 3 days after abruptly stopping SSRI. Dizziness, N/V, fatigue, lethargy, flu-like symptoms
Anxiety, crying, irritability are not uncommon

58
Q

Which SSRI does not require tapering due to its long half life?

A

Fluoxetine

59
Q

Use of what medication concurrently with Lamotrigine will cause its levels to be low

A

Oral contraceptives

*Lamotrigine may also induce the metabolism of OCPs potentially rendering them less effective

60
Q

Most common EKG change in about 30 % of patients on Lithium

A

t wave inversion/depression

61
Q

What class of drugs/drugs can increase lithium levels owing to decreased lithium clearance

A
Thiazide diuretics 
Ethacrynic acid
Spironolactone
Triamterine
NSAIDs
Metronidazole
Tetracycline
62
Q

Most effective treatment of OCD

A

Clomipramine

63
Q

Patient with moderate response to SSRI for treatment of OCD…what is viable option for augmenting tx with SSRI?

A

Risperidone

64
Q

Management for performance anxiety

A

Propranolol

65
Q

Severe side effect of Lamotrigine

A

Rash that can turn into SJS

66
Q

Opisthotonos

A

Spasm of neck and back that causes patient to arch forward

67
Q

Oculogyric crisis

A

spasm of extraocular muscles, resulting in patient looking up and unable to look down.

68
Q

Pleurothotonos (Pisa syndrome)

A

Leaning posture induced by spasm of torso muscles

69
Q

torticollis

A

spasm of neck muscles that usually brings the neck to one side or another but may pull it forward or backward

70
Q

Antidepressant approved for treatment of depression and neuropathic pain

A

Duloxetine

71
Q

Antidepressants that do not cause sexual side effects

A

Mirtazapine

Buproprion

72
Q

Patient on warfarin with anxiety…only class of drugs for anxiety treatment that won’t interact with warfarin?

A

Benzodiazepines

73
Q

Anticonvulsant used in treatment of bulimia and binge eating disorder

A

Topiramate

74
Q

Risk of using topiramate

A

Renal stones

Cognitive impairment, word-find difficulty, short-term memory problems

75
Q

Retrograde ejaculation

A

Thioridazine

76
Q

Rabbit syndrome

A

Risperidone

*Repetitive rapid movements of mouth but not tongue

77
Q

Pigmented retinopathy

A

Thioridazine

78
Q

Obstructive jaundice

A

Chlorpromazine

79
Q

Orthostatic hypotension

A

Chlorpromazine

Clozapine

80
Q

How long after last drink does delirium tremens usually develop?

A

3 days

81
Q

Hyponatremia

A

Oxcarbazepine

82
Q

Testamentary capacity

A

Level of competence required to make a legally valid will

83
Q

Current basis for establishing an insanity defense

A

American Law Institute Test (Model Penal Code)