Lange Q + A Flashcards

1
Q

Fregoli delusion

A

Familiar people assume the guise of strangers (opposite of capgras)

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2
Q

Cotard Syndrome

A

Where people think they are losing things, as well as blood, intestines, or meaning in the world.

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3
Q

Common symptom of prodrome for schizophrenia

A

Progressive social withdrawal.

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4
Q

Features of schizophrenia presentation that portend good prognosis?

A

Acute onset of symptoms, predominantly positive symptoms, later age at presentation, female gender

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5
Q

How to treat catatonia?

A

Benzodiazepines.

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6
Q

Relative contraindication to ECT?

A

Space occupying mass in the skull which can cause increased ICP, also recent MI (within 3 months).

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7
Q

How to treat alcohol withdrawal?

A

Benzos:

Oxazepam and lorazepam because they don’t require metabolism in the liver.

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8
Q

Mortality of DT?

A

30%

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9
Q

Hypomania vs mania

A

Hypo mania doesn’t result in hospitalization or cause work dysfunction.

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10
Q

What stroke will cause depression? Mania?

Obsessive compulsive symptoms??

A

Left frontal for depression, right frontal for mania, diffuse frontal for OCD.

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11
Q

Which NT is depleted in CSF of suicide victims?

A

5HT metabolites

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12
Q

Which treatment of depression has the HIGHEST rates of causing mania?

A

Tricyclic antidepressants. Slightly higher than SSRI.

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13
Q

How to best treat atypical depression?

A

Phenelzine and other MAOIs.

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14
Q

How to treat DT?

A

IV benzodiazepines

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15
Q

Thioridizine side effect?

A

Retinal pigmentation, can lead to permanent blindness

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16
Q

Strongest benzodiazepine?

A

Klonopin

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17
Q

How to treat panic disorder?

A

SSRI.

Buspirone can only be used to treat GAD.

18
Q

How does NSAID use affect lithium levels?

A

NSAID use can increase lithium levels, but aspirin does not.

19
Q

If patient has NO response to SSRI, what should you do?

A

Switch to another SSRI

20
Q

If patient has partial response to SSRI, what should you do?

A

Switch or augment with T3 or Lithium.

21
Q

How to reverse or slow tardive dyskinesia?

A

Clozapine.

22
Q

What does giving a pregnant woman an SSRI do to the baby?

A

Persistent pulmonary hypertension of the newborn.

23
Q

Treatment of anorexia vs bulimia?

A

Anorexia shouldn’t be treated with anything, bulimia responds well to SSRI.

24
Q

Discontinuation syndrome strongest with what SSRI?

A

Paroxetine.

25
Q

What medications reduce effectiveness of lamotrigine?

A

Oral contraceptives.

26
Q

Lithium cardiac changes?

A

T wave depression

27
Q

How to augment response to clomipramine in refractory OCD?

A

Add risperidone

28
Q

What quality makes clozapine so effective at treating psychosis

A

Significant antagonism at the D4 receptor.

29
Q

Which class of antidepressants cause the most orthostatic hypotension?

A

Tricyclic Antidepressants

30
Q

How to treat delirium in elderly? Delirious agitation?

A

Risperidone –> haloperidol (IM).`

31
Q

Why isn’t flumazenil used in an emergency setting without eliciting history of benzodiazepine overdose?

A

Because it can lower seizure threshold.

32
Q

How to treat bulimia refractory to SSRI?

A

Topiramate

33
Q

Common side effect of TMS?

A

Headache

34
Q

Which medication can cause pancreatitis?

A

Depakote

35
Q

How long to treat unipolar depression with SSRI?

A

6-12 months

36
Q

How to treat clozapine drooling? Tachycardia?

A

Clonidine, propranolol

37
Q

How to best treat middle insomnia?

A

Zaleplon

38
Q

Topiramate side effect

A

Renal stones and cognitive slowing

39
Q

How are suicidal children most likely to kill themselves?

A

Pill ingestion.

40
Q

Desmopressin side effect?

A

Headache