Lange Q + A Flashcards

1
Q

Fregoli delusion

A

Familiar people assume the guise of strangers (opposite of capgras)

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2
Q

Cotard Syndrome

A

Where people think they are losing things, as well as blood, intestines, or meaning in the world.

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3
Q

Common symptom of prodrome for schizophrenia

A

Progressive social withdrawal.

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4
Q

Features of schizophrenia presentation that portend good prognosis?

A

Acute onset of symptoms, predominantly positive symptoms, later age at presentation, female gender

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5
Q

How to treat catatonia?

A

Benzodiazepines.

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6
Q

Relative contraindication to ECT?

A

Space occupying mass in the skull which can cause increased ICP, also recent MI (within 3 months).

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7
Q

How to treat alcohol withdrawal?

A

Benzos:

Oxazepam and lorazepam because they don’t require metabolism in the liver.

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8
Q

Mortality of DT?

A

30%

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9
Q

Hypomania vs mania

A

Hypo mania doesn’t result in hospitalization or cause work dysfunction.

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10
Q

What stroke will cause depression? Mania?

Obsessive compulsive symptoms??

A

Left frontal for depression, right frontal for mania, diffuse frontal for OCD.

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11
Q

Which NT is depleted in CSF of suicide victims?

A

5HT metabolites

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12
Q

Which treatment of depression has the HIGHEST rates of causing mania?

A

Tricyclic antidepressants. Slightly higher than SSRI.

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13
Q

How to best treat atypical depression?

A

Phenelzine and other MAOIs.

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14
Q

How to treat DT?

A

IV benzodiazepines

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15
Q

Thioridizine side effect?

A

Retinal pigmentation, can lead to permanent blindness

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16
Q

Strongest benzodiazepine?

A

Klonopin

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17
Q

How to treat panic disorder?

A

SSRI.

Buspirone can only be used to treat GAD.

18
Q

How does NSAID use affect lithium levels?

A

NSAID use can increase lithium levels, but aspirin does not.

19
Q

If patient has NO response to SSRI, what should you do?

A

Switch to another SSRI

20
Q

If patient has partial response to SSRI, what should you do?

A

Switch or augment with T3 or Lithium.

21
Q

How to reverse or slow tardive dyskinesia?

A

Clozapine.

22
Q

What does giving a pregnant woman an SSRI do to the baby?

A

Persistent pulmonary hypertension of the newborn.

23
Q

Treatment of anorexia vs bulimia?

A

Anorexia shouldn’t be treated with anything, bulimia responds well to SSRI.

24
Q

Discontinuation syndrome strongest with what SSRI?

A

Paroxetine.

25
What medications reduce effectiveness of lamotrigine?
Oral contraceptives.
26
Lithium cardiac changes?
T wave depression
27
How to augment response to clomipramine in refractory OCD?
Add risperidone
28
What quality makes clozapine so effective at treating psychosis
Significant antagonism at the D4 receptor.
29
Which class of antidepressants cause the most orthostatic hypotension?
Tricyclic Antidepressants
30
How to treat delirium in elderly? Delirious agitation?
Risperidone --> haloperidol (IM).`
31
Why isn't flumazenil used in an emergency setting without eliciting history of benzodiazepine overdose?
Because it can lower seizure threshold.
32
How to treat bulimia refractory to SSRI?
Topiramate
33
Common side effect of TMS?
Headache
34
Which medication can cause pancreatitis?
Depakote
35
How long to treat unipolar depression with SSRI?
6-12 months
36
How to treat clozapine drooling? Tachycardia?
Clonidine, propranolol
37
How to best treat middle insomnia?
Zaleplon
38
Topiramate side effect
Renal stones and cognitive slowing
39
How are suicidal children most likely to kill themselves?
Pill ingestion.
40
Desmopressin side effect?
Headache