Lactation & Human Milk Flashcards

1
Q

When does lobules gradually appear becoming distinct?

A

12-18 months after 1st menstrual period

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2
Q

What happens with breast maturation during 1st trimester?

A

small ducts proliferate to surface cells

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3
Q

What happens with breast maturation during 2nd trimester?

A

small ductules form large lobules

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4
Q

What happens with breast maturation during 3rd trimester?

A

milk-producing cells dilate to prepare for lactation

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5
Q

What composes 10% of the total milk CHO and is predominantly composed of lactose-N-tetraose and its monofucosylated derivatives?

A

Human Milk Oligosaccharides (HMOs)

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6
Q

This determines a mother’s ability to make certain abundant HMOs

A

Secretor status

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7
Q

Responsible for the composition and functional properties of glycans in mucosal tissues and bodily secretions, including human milk

A

FUT2 gene

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8
Q

Milk volume

A

600-900 mL/day

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9
Q

The primary carbohydrate which comprises approximately 80% of the total carbohydrate load

A

Lactose

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10
Q

When does transitional milk becomes mature milk

A

end of 1st month

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11
Q

Phosphorus-containing proteins that occur ONLY
in milk

A

Casein

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12
Q

Thin liquid of milk remaining after the curd (casein) & cream have been removed; contains lactoferrin & lactalbumin

A

Whey protein

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13
Q

How many CHON per 100mL of milk

A

0.8-0.9 g CHON

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14
Q

Amino acid quality of mature milk

A
  • lower in Met, rich in Cys
  • lower Phe & Tyr
  • rich in Taurine
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15
Q

Stimulates growth of bifidobacteria

A

bifidus factor

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16
Q

Acts against bacterial invasion of the mucosa

A

Immunoglobulins

17
Q

Binds Fe & inhibits bacterial multiplication

A

Lactoferrin

18
Q

Inhibits intracellular viral replication

A

Interferon

19
Q

Kills bacteria through destruction of cell wall

A

Lysozome

20
Q

makes B12 unavailable for bacteria

A

B12-binding CHON

21
Q

Synthesizes IgA

A

Lymphocytes

22
Q

Synthesizes lactoferrin, lysozome, etc.

A

Macrophages

23
Q

Energy needed for daily milk production

A

560kcal

24
Q

Daily CHON intake

A

15-20g