Lactation and Prolactinomas Flashcards

1
Q

What cells release prolactin?

A

Lactotroph cells in the pituitary gland

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2
Q

What can inhibit prolactin release?

A

dopamine

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3
Q

What can stimulate prolactin release?

A

5HT (serotonin), TRH, oxytocin

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4
Q

Where is oxytocin synthesised?

A

Synthesised in hypothalamic magnicellular neurons

  • Supraoptic nucleus
  • Paraventricular nucleus
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5
Q

How can NFA mimic prolactinomas?

A
  • compression of the pituitary stalk

- blocks the control of prolactin release from normal lactrotrophs

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6
Q

MacroPRLoma

A

tumour over 1cm

visual field defects

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7
Q

primary hypothyroidism

-test results

A
  • low FT4

- TSH always high

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8
Q

What should thyroid function tests show in post-menopausal women?

A

Should show high LH and FSH

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