Lactation and Prolactinomas Flashcards
1
Q
What cells release prolactin?
A
Lactotroph cells in the pituitary gland
2
Q
What can inhibit prolactin release?
A
dopamine
3
Q
What can stimulate prolactin release?
A
5HT (serotonin), TRH, oxytocin
4
Q
Where is oxytocin synthesised?
A
Synthesised in hypothalamic magnicellular neurons
- Supraoptic nucleus
- Paraventricular nucleus
5
Q
How can NFA mimic prolactinomas?
A
- compression of the pituitary stalk
- blocks the control of prolactin release from normal lactrotrophs
6
Q
MacroPRLoma
A
tumour over 1cm
visual field defects
7
Q
primary hypothyroidism
-test results
A
- low FT4
- TSH always high
8
Q
What should thyroid function tests show in post-menopausal women?
A
Should show high LH and FSH