Labs Flashcards
the test has a low rate of false negatives
sensitive test
this test is used is used to measure the diseased cohort (sick patient and you are looking for cause)
sensitive test
this test has a low rate of false positives (used on healthy population/pha labs)
specific test
formula for T 1/2 beta ?
(0.7 x Vd)/clearance
what happens to the vessel when lesion at site?
vasoconstriction distal
vasodilation proximal
increased WBC to localized area of injury
vasodilation caused by prostacyclins and PGE2 to mobilize WBC to the site of injury
vasoconstriction caused by thromboxane and leukotrienes to prevent spread of infection to systemic
triad for inflammatory process?
increased WBC CRP ESR
Where is crp synthesized?
liver
because of inflammatory response
cytokines
best biomarker for renal function?
creatinine excreted entirely by kidneys and is directly proportional to renal excretory function.
inversely proportional to GFR
normal GFR?
125ml/min
where is the majority of calcium found
bones
If major Duckwork gave double the dose of insulin what would oppose the effects?
glucagon
epinephrine
cortisol
GH
What is anion gap?
normal 8-16
measure of plasma anions chloride and bicarb
lactic acid using up bicarb
Na - Cl + bicarb
anion gap =ketoacidosis, lactic acidosis, renal failure
non anion gap= mudd butt, renal tube acidosis, renal failure
Important roles for calcium?
neurotransmitter
cardiac myocytes inotropy and chronotropy
muscle contraction
coagulation
anesthetic gas that causes birth defect
nitrous oxide
methionine
who is the false calcium?
what does it do?
magnesium
see decreased physiologic responses associated with Ca
relaxes smooth muscle