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Summer 1 > Labor & Delivery (KEY POINTS) > Flashcards

Labor & Delivery (KEY POINTS) Flashcards

1
Q

What is the role of calcium during labor?

A

Controls uterine contraction

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2
Q

What action has an inhibitory effect on uterine contraction?

A

Stimulation of ATP-sensitive potassium channels

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3
Q

What 5 drugs promote uterine contractions?

A 
Oxytocin 
PGE E2
Carboprost 
Mifepristone 
Methylergonovine
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4
Q

Which 3 drugs control postpartum hemorrhage?

A

Oxytocin

Carboprost

Methylergonovine

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5
Q

Which 2 drugs promote cervical ripening?

A

PGE E2

Oxytocin

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6
Q

Describe the role of mifepristone

A

Progesterone antagonist

Terminates pregnancy up through day 49 of gestation

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7
Q

Which drug induces labor?

A

Oxytocin DUH!

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8
Q

What are the 3 forms of PGE E2 available?

A

Gel

Vaginal insert

Vaginal suppository

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9
Q

What form of PGE E2 is used for termination of pregnancy?

A

Vaginal suppository

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10
Q

What are ADEs of PGE E2?

A

N/V, +/- fever

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11
Q

What is carboprost?

A

Methylated analogue of PGF2alpha

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12
Q

Which drug causes STRONG uterine contractions?

A

Carboprost

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13
Q

What is carboprost used for?

A

Postpartum hemorrhage (MC)

Induce uterine emptying

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14
Q

What is carboprost NOT used for?

A

Elective induction of uterine contractions w/ viable infant

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15
Q

What are ADEs of carboprost?

A
  • Bronchospasm (contraindicated in asthma)
  • HTN
  • V/D
  • “Choking”
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16
Q

Besides uterine contractions, which drug also causes vasoconstriction?

A

Methylergonovine

17
Q

Which type of drugs suppress uterine contractions?

A

Tocolytic agents (Terbutaline, nifedipine, NSAIDs, MgSO4)

Prevents delivery of premature infant

18
Q

What drug class does terbutaline belong to?

A

Beta2 agonist

19
Q

What are the ADEs of terbutaline?

A 
Syndrome of tachy
Pulmonary edema
Metabolic acidosis
Hypokalemia
Hypotension
20
Q

Which drug should not be used > 5-7 days in women in preterm labor?

A

MgSO4 (Category D drug)

Can lead to hypocalcemia, osteopenia, & bone fx in newborn

21
Q

What are ADEs of MgSO4?

A

High serum Mg levels –> weakness, paralysis, resp. failure, & hypotension

22
Q

What will impair the elimination of Mg?

A

Renal insufficiency

23
Q

What procedure is used to lower Mg levels in severe toxicity?

A

Hemodialysis

24
Q

Which drugs cause uterine relaxation?

A

Terbutaline

NSAIDS (Indomethacin, ibuprofen)

25
Q

What are ADEs of NSAIDs (w/ respect to the baby) ?

A

Decreased GFR

Narrowed/closed fetal ductus arteriosis

26
Q

What is given IM weekly to women w/ hx of recurrent miscarriage @ > 20wks?

A

Hydroxyprogesterone caproate

Summer 1 (16 decks)

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