Lab1: Virus Imaging Flashcards
What is the first virus to be discovered?
Tabaco mosaic virus (TVM)
What is the main structure of the virus?
Helical structure
What is one strand of RNA wrapped around?
A sheath of protein
Of what is made the protein coat?
Small proteins that stacks in a cylindrical chimney
What are the 4 proteins that encodes the single RNA strand?
-2 that replicate viral RNA
-1 that transports the RNA from cell to cell
-1 capsid protein
Does the coat protein needs to be removed once the virus is inside the cell?
Yes
Capsid protein releases RNA in a calcium high-level or low-level of calcium?
Low-level (inside the cell)
What are the 6 steps for releasing RNA in TMV viruses?
1-capsid protein repel one another in low-calcium conditions inside the cells
2-loosen the first capsid protein
3-Releasing DNA
4-Ribosomes moves down the strand — join amino acids together
5-Create the first set of viral proteins
6-displace the remaining capsid proteins
What are the monomer and polymer of nucleic acid?
Monomer: nucleotide
Polymer: nucleic acids (DNA or RNA)
Where is glycoprotein located on Ebola virus?
Studded on the membrane
What is the task of Ebola glycoproteins?
To get Ebola genome inside the cell by binding to receptors on cell surface
In the Measles virus, where is located the nucleocapsid?
Inside the viral membrane
What is the function of nucleocapsid in the measles virus?
Chaperon the process of replication and transcription by providing a ready site for binding of the polymerase complex
What is the main structure of measles virus?
Nucleoprotein + strand of RNA
What is the most important receptor on the SARS Cov virus?
The receptor binding protein domain (RBD)