Lab review Flashcards
Meds that cause high K
potassium supplements ACEI ARB Bactrim Spironolactone Amloride
Medical conditions or lab issues that cause high K
CKD or AKI Hemolysis/bleeding Hemolyzed specimen- bad blood draw Tumor lysis syndrome Metabolic acidosis Insulin deficiency Tissue breakdown - rhabdo
BUN ratio 30:1 means
GI bleed
BUN ratio 20:1 means
prerenal AKI -
dehydration
decreased effective circulating volume (cirrhosis, CHF, nephrotic syndrome), shock/hypotension, hemorrhage
MCV >100 causes
vit b12 def or folate def alcohol liver dz myelodysplastic syndrome hypothyroidism meds! allopurinol, immunosuppressants, Bactrim, h2 blockers, PPIs, metformin
MCV <80 causes
Iron deficiency anemia thalassemia lead poisoning copper def zinc poisoning GI bleeding
Increased total bili causes
liver dz
hemolytic anemia
Increased platelet causes
reactive thrombocytosis - infection - blood loss, anemia - non-infectious inflammation - post-splenectomy blood malignancies- p vera, CML, MDS, AML familial thrombocytosis
Low magnesium causes
GI losses- diarrhea > vomiting
Meds- PPI usage, loop & thiazide diuretics
Alcohol use disorder
Post-transplant patients
Increased WBC causes
infection inflammation neoplasms meds- glucocorticoids, catecholamines (epi), lithium smoking stress/exercise obesity
AST predominant
alcohol hepatitis
ALP predominant
biliary obstruction or bone
if bili elevated= liver/gallbladder obstruction
ALT predominant
drug induced liver injury
Low K causes
GI losses- diarrhea Thiazide & loop diuretics Hyperaldosteronism Hypomagnesemia Insulin, beta agonist, alkalosis- drives K into cells Sweat Dialysis
Elevated D dimer
DVT/PE DIC COVID Infection/sepsis Surgery/trauma MI/CVA Liver dz Renal dz Malignancy Pregnancy