Lab Integumentary System Flashcards
is considered an organ system because it consists of multiple organs, the skin and its accessory organs
integument
The skin has many functions, most concerned with
Protection
The skin has two distinct regions
Superficial epidermis and the dermis
Immediately deep to the dermis is the — or hypodermis,
Subcutaneous layer
Structurally, this is a keratinized stratified squamous epithelium consisting of four distinct cell types and four or five distinct layers.
Epidermis
Cell types of epidermis
Keratinocytes, melanocytes, dendritic cell, and tactile epithelial cell
The most abundant epidermal cells, their main function is to produce keratin fibrils
Keratinocytes
is a fibrous protein that gives the epidermis its durability and protective capabilities.
Keratin
Spidery black cells that produce the brown-to-black pigment called melani
Melanocytes
Also called Langerhans cells, these cells arise from the bone marrow and migrate to the epidermis.
They ingest foreign substances and play a key role in acti-vating the immune response.
Dendritic cells
Occasional spiky hemispheres that, in combination with sensory nerve endings, form sensitive touch receptors located at the epidermal-dermal junction.
Tactile epithelial cells:
The outermost layer consisting of 20–30 layers of dead, scalelike keratinocytes. They are constantly being exfoliated and replaced by the division of the deeper cells.
Stratum corneum (horny layer)
Present only in thick skin. A very thin transparent band of flattened, dead keratinocytes with indistinct boundaries
Stratum lucidum (clear layer)
A thin layer named for the abundant granules its cells contain. These granules are (1) lamellar granules, which contain a waterproofing glycolipid that is secreted into the extracellular space; and (2) keratohyaline granules, which help to form keratin in the more superficial layers. At the upper border of this layer, the cells are beginning to die.
Stratum granulosum (granular layer)
Several layers of cells that contain thick, weblike bundles of intermediate filaments made of a pre-keratin protein. The cells in this layer appear spiky because when the tissue is prepared, the cells shrink, but their desmosomes hold tight to adjacent cells. Cells in this layer and the basal layer are the only ones to receive adequate nourishment from diffusion of nutrients from the dermis.
Stratum spinosum (spiny layer)