Lab Five Flashcards
What are the anatomical relationships of the esophagus in the mediastinum?
The esophagus lies posterior to the trachea, anterior to the vertebral column, posterior to the heart, medial to the lungs, and the descending aorta lies slightly to the left-posterior side.
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At what level does the esophagus pass through the diaphragm?
The esophageal hiatus is located at T10. The abdominal portion of the esophagus is about 1 inch long and enters the stomach posterior to the seventh costal cartilage.
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Describe the location of the submandibular gland.
The submandibular gland may be found under the floor of the mouth and along the medial surface of the mandible.
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Where are taste buds found?
Taste buds are mainly found along the sides of the large circumvallate papillae and along the tops and sides of the fungiform papillae. There are approximately five taste buds per fungiform papilla, compared to almost one hundred per circumvallate papilla.
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What is the organization of the muscle layers of the stomach, along with their cellular makeup?
1. Inner oblique
2. Middle circular
3. Outer longitudinal
These three layers are all made up of smooth muscle.
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Describe the location of the sublingual gland.
The sublingual gland may be found anterior to the submandibular gland just below the tongue.
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What kind of cells make up the submandibular glands?
The submandibular glands are a mix between serous and mucous cells.
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Describe the histology of the taste buds.
The taste buds are composed of three main components: gustatory cells (gustatory receptors), supporting cells, and basal stem cells.
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Describe the histological organization of the stomach.
The mucosal lining of the stomach consists of simple columnar epithelium that is composed mainly of mucus surface cells. These epithelial cells invaginate the mucosal surface, forming gastric pits (lined with simple columnar cells). Each gastric pit leads into a gastric gland that extends into the lamina propria of the mucosal membrane.
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What is the pyloric sphincter?
The middle circular layer thickens to form the pyloric sphincter. This sphincter acts as a valve to control the movement of chyme from the stomach to the small intestine (duodenum).
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What kind of cells make up the parotid gland?
The parotid gland is mainly comprised of serous cells.
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What kind of cells make up the sublingual gland?
The sublingual gland is mainly composed of mucous cells.
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What are the four layers of the esophageal wall along with their characteristics?
-
Mucosa
- Made of stratified squamous epithelium
- Lamina propria (loose connective tissue)
- Muscularis mucosae (smooth muscle)
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Submuscosa
- Dense irregular connective tissue
- Mucus-secreting glands
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Muscularis externa
- Made of an inner circular layer
- Made of an outer longitudinal layer
- Upper 1/3 is skeletal muscle
- Middle 1/3 is a mix of skeletal/smooth muscle
- Lower 1/3 is smooth muscle
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Adventitia
- Dense, fibrous connective tissue
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What is the functional importance of mucosal neck cells, parietal cells, and chief cells?
- Mucosal neck cells - produces and secretes mucous that protects the lining of the pits from acidic erosion.
- Parietal cells - produce and secrete HCl and intrinsic factor (B12 absorption).
- Chief cells - produce and secrete pepsinogen that is converted by HCl into pepsin, an active enzyme that breaks down proteins into their monomers amino acids.
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Which cranial nerve innervates the skeletal muscles of the tongue?
The hypoglossal nerve (CN XII) is responsible for the innervation of the skeletal muscle of the tongue. However, the palatoglossus is an exception and is innervated by the pharyngeal branch of the Vagus nerve (CN X).
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