Lab Chapter 9: Integumentary System Flashcards
Rule of Nines
Quick method of estimating the percent of body surface area affected by burns. Each major area represents 9% of the total body surface area
First Degree Burn
- Only surface of epidermis is damaged
- Redness results from inflammation of damaged tissues
- Healing occurs within one week
- No scarring occurs
- e.g. sunburn
Second Degree Burn
- Epidermis & often part of dermis is damaged
- accessory structures (hair, gland, etc.) are intact
- blistering, pain and swelling occur
- healing occurs from accessory structures & edge of burn
- healing occurs in 2 weeks (epidermis only) up to 2 months (dermis involved)
- some scarring may occur
Third Degree Burn
- Epidermis & dermis destroyed; hypodermis & tissues beneath damaged
- usually painless due to nerve destruction
- accessory structures and blood vessels destroyed; healing cannot occur
- skin grafting is usually required
- infections likely and life-threatening
Basal Cell Carcinoma
- most common type
- origin: Stratum basale
- rarely metastasizes
- small, shiny bump on skin surface; as bump enlarges, often develops a central depression and beaded “pearly” edge
- least dangerous
Squamous Cell Carcinoma
- Origin: stratum spinosum
- can metastasize to lymph nodes if untreated
- lesions are raised, reddened, and scaly; usually appear on scalp, ears, lower lip, or back of the hand
Malignant Melanoma
- most deadly type of skin cancer
- origin: often arises from the melanocytes of a pre-existing mole
- metastasizes very quickly & drug resistant
- early detection is crucial for survival
ABC Rule
A for Asymmetry: irregular in shape
B for Border: borders are unclear or irregular
C for Color: generally mottled with many colors
D for Diameter: growths greater than 5mm in diameter
E for Elevation: raised above the skin surface
Stratum Corneum
outermost layer of both thick and thin skin; consists of 15 to 30 layers of dead, keratinized cells; protects the underlying cells and helps to minimize water loss from body
Stratum Lucidum
translucent layer immediately deep to s. corneum; found in thick skin only
Stratum Granulosum
Deep to s. lucidum in thick skin (s. corneum in thin skin); three to five cell layers thick; keratin formation begins in this layer and cells begin to die
Stratum Spinosum
Thicker layer just deep to s. granulosum; cells in this layer shrink during histological preparation, giving them characteristic “spiny” look that lends this layer its name
Stratum Basale (germinativum)
deepest layer of epidermis; single layer of cells located adjacent to dermis; mitotically active, rapidly replacing cells of stratum corneum that are constantly being shed
Epidermis
composed mostly of keratinized stratified squamous epithelium and forms the outermost protective shield of the body; composed of several strata (5 in thick skin & 4 in thin skin)
Dermis (corium)
composed mainly of connective tissue; located under epidermis