Lab 7 Flashcards

1
Q

Generated by excitable cells, rapid reversal of polarity

A

Action potential

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2
Q

Rising phase of action potential

A

Depolarization

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3
Q

Falling phase of action potential

A

repolarization

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4
Q

Undershoot of AP

A

Hyperpolarization

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5
Q

Muscle cells of the heart, a phase of intermediate voltage precede the falling phase , extending duration of AP

A

Plateau phase

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6
Q

Action potential is an —–

A

All or none process

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7
Q

Specific information transmitted by the neurons encoded in the

A

Frequency of action potential and their velocity of conduction

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8
Q

When there is no electrical activity

Cell difference across the cell membrane

A

Resting potential

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9
Q

In resting potential is it negative inside or outside?

A

Negative inside

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10
Q

Potential difference or the transmembrane potential in neurons at rest

A

-70mv

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11
Q

These contributes to electrical activity of various cell bodies

A

Electrochemical pump, voltage gated channels Na, K leak channels , differential distribution of permeable and non permeable ions

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12
Q

AP, of a nerve can be visualized on a computer screen through

A

Chart or scope software

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13
Q

Which leg is dissected in frogs

A

Sciatic nerve

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14
Q

Where does the nerve placed?

A

Nerve chamber

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15
Q

Is a sciatic nerve compound or not

A

Compound nerve

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16
Q

Thick myelinated fibers have ____ thresholds and conduct impulse ____

A

Lower , faster

17
Q

Unmyelinated or smaller diameter fibers which need strong stimulus

A

High threshold and slow conduction

18
Q

2 peaks

A

Compound action potential

19
Q

How does resolution increase?

A

Increasing the distance between the stimulating and recording electrodes and using sub maximal stimuli

20
Q

What does the increasing of distance significant for

A

Nerves has more time to pull away and separate from the action potential of slower conducting nerves

21
Q

Strength increase =

A

Current begins to excite larger areas of the axon

22
Q

Result of using sub maximal stimuli

A

AP occurs more quickly and the latency of stimulation decreases

23
Q

Voltage at which neuron is sufficiently stimulated (depolarizer) to fire action potential

A

Threshold

24
Q

At some stimulus voltage, all neurons reach threshold and fire all action potentials
Further increase will NOT recruit more axons to fire

A

Maximum response

25
Q

Strength of stimulus is____ as the duration of stimulus

A

Reverse proportional

26
Q

The minimal voltage over the longest duration of current flow milliseconds

A

Rheobase

27
Q

Significance of rheobase

A

Progressive increase in pulse duration is no longer associated with a progressive decrease in voltage

28
Q

The duration needed to produce a response at twice the rheobase strength

A

Chronoaxie

29
Q

Indicative of excitability of differ t nerves dependent of Na channels

A

Chronoaxie

30
Q

Significance of chronoaxie

A

If 2 nerves with the be same rheobase, chronoaxie the stimulus duration corresponding to twice the rheobase can give an indication of their relative excitabilities

31
Q

Equation of conduction velocity

A

cv = d/t (cm/s)

32
Q

Deflection caused by application of the voltage to the nerve

A

Stimulus artifact

33
Q

Often studied by measuring difference between the sites of 2 electrodes

A

Biolectrical phenomena

34
Q

Dropped on the nerve and increases the speed of conduction of AP

A

Warm ringers solution

35
Q

Decrease conduction velocity

A

Cold fingers solution

36
Q

Increasing the K+ ion concentration outside the axon will

A

Increase the rate at eh in potential will be generated or propagated

37
Q

Reason of KCl increase AP

A

Higher k+ concentration outside will prevent k efflux making inside more positive and closer to depolarization in shorter time

38
Q

Blocks voltage gated Na+ channels will inhibit propagation of AP

A

Lidocaine