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PDF LEC > LAB > Flashcards

LAB Flashcards

1
Q

semisolid preparations applied on skin and mucous membranes

A

OINTMENTS (Unguentum)

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2
Q

Ointment Bases

A
  1. Oleaginous Base/ Hydrocarbon Base
  2. Absorption Base
  3. Water-removable Base
  4. Water-soluble Base
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3
Q

It is Greasy, Anhydrous, Emollient, Occlusive effect, Non-water washable

A

OLEAGINOUS BASES

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4
Q

mixture of semisolid hydrocarbon from petrolatum

A

Petrolatum USP / Yellow Petrolatum / Petroleum Jelly

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5
Q

Bleached form of Petrolatum USP

A

White Petrolatum

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6
Q

From honeybees/ honeycomb of Apis mellifera

A

YELLOW WAX / BEESWAX

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7
Q

Bleached form of wax

A

WHITE WAX

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8
Q

Yellow petrolatum + yellow wax

A

Yellow Ointment / Simple Ointment

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9
Q

White petrolatum + white wax

A

White Ointment

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10
Q

It is Greasy, Anhydrous, Emollient, Occlusive effect, Non-water washable
(can absorb small amount of water > will form w/o)

A

ABSORPTION BASES

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11
Q

Contains:
- White wax
- White Petrolatum
- Stearyl Alcohol
- Cholesterol

A

HYDROPHILIC PETROLATUM (AQUAPHOR)

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12
Q

from wool of sheep (Ovis aries)
- 0.25% moisture

A

ANHYDROUS LANOLIN

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13
Q

has 25% moisture

A

HYDROUS LANOLIN

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14
Q
  • o/w emulsion
  • Non-greasy, non-occlusive, water washable
  • Can be diluted with large amount of water
A

WATER-REMOVABLE BASES

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15
Q

No oleaginous component
- lipid-free ; greaseless; non-occlusive; water-washable
- For incorporation of solid substances

A

WATER-SOLUBLE BASES

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16
Q

MW <600

A

CLEAR, COLORLESS LIQUID

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17
Q

MW >1000

A

WAX-LIKE WHITE SOLID

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18
Q

MW 600-1000

A

SEMISOLID

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19
Q

use of ointment roller mills to mix heat-sensitive ointment bases.

A

INCORPORATION

20
Q

use of steam-jacketed kettles to melt anhydrous ointment bases and cooling gradually until congealed

A

FUSION

21
Q

More liquid in consistency than ointment therefore more spreadable to the skin

A

CREAMS

22
Q

Semisolid dosage form in which the drug is dissolved or dispersed in either o/w or w/o emulsion base or any type of water-removable base

applied to larger areas of skin

A

CREAMS

23
Q

Water will evaporate and a thin film of stearic acid will remain

A

VANISHING CREAM

24
Q

COMPONENTS:
-Large percentage of H2O
-Humectant (polyhydric alcohol) -Stearic acid

A

VANISHING CREAM

25
Q

w/o base

A

COLD CREAM / PETROLATUM ROSE WATER OINTMENT

26
Q

Clear, colorless dispersion systems which are rendered jelly-like by the addition of a gelling agent

A

GELS

27
Q

Jelly like consistency - Thixotropy

A

GELS

28
Q

Semisolid preps applied on the skin containing a larger proportion of solid materials (>25%)

-Stiffer than ointments

A

PASTE

29
Q

Topical protectant (treatment & protection of diaper rash)

A

ZnO paste

30
Q

antipruritic that contains ZnO

A

CALAMINE LOTION

31
Q

are applied to the skin for the long term. They are melted before application, cooled to slightly above body temperature and applied to the affected area with a fine brush.

A

GLYCEROGELATIN

32
Q

treatment of varicose ulcers

A

ZINC GELATIN BOOT

33
Q

Solid masses inserted into a body cavity in which they melt at body temperature or dissolve into the aqueous secretions of the body orifice.

A

SUPPOSITORY

34
Q
  • It is given when oral route is not possible: coma, vomiting, infants
A

SUPPOSITORIES

35
Q

Suppository base used in Rectal, Urethral
-melts at body temperature

A

OLEAGINOUS BASES

36
Q
  • from seeds of Theobroma cacao
  • most common base for rectal suppositories
    -solid @32°C ; melts @ 34-35°C
A

COCOA BUTTER

37
Q

more than 1 crystal form

A

POLYMORPHISM

38
Q

Mixture of triglycerides. From coconuts

A

WECOBEE

39
Q

Mixture of saturated fatty acid; major component: Lauric acid

A

WITEPSOL

40
Q

Suppository based used for Vaginal suppository
-Aqueous environment

A

WATER-SOLUBLE / MISCIBLE

41
Q

most common base for pessaries

A

GLYCERINATED GELATIN

42
Q

alternative base for pessaries

A

POLYETHYLENE GLYCOL

43
Q

oldest; simplest method of preparation

  • disadvantage: variance in appearance
A

HAND MOLDING

44
Q
  • avoids heat
  • problem: air entrapment; weight variation
A

COMPRESSION MOLDING

45
Q
  • most common method
  • base is melted and poured to molds - Lubricant is needed (mineral oil)
A

POUR / MELT MOLDING

PDF LEC (4 decks)

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