Lab 12 Flashcards
What is urine composed of
Substances from the blood plasma that have been filtered out
Nitrogenous waste by product of protein metabolism
Urea
Nitrogenous waste by product of nucleic acid metabolism
Uric acid
When oxygen is low the kidney will secrete this hormone to stimulate RBC production
Erythropoietin
The functional unit of the kidney
Nephron
What are the three major functions of the kidney
Filtration
reabsorption
secretion
This major function of the nephron is bulk movement of fluid from the blood into the nephron
Takes place in glomerulus
Filtration
This function of the nephron is returning substances from the filtrate back to the blood
Reabsorption
This function of the nephron is movement of individual ions from the blood into the nephron tubule (H+ K+)
Secretion
The innermost layer of the glomerular filter is made up of fenestrations of of what
Capillary endothelium
The middle layer of the glomerular filter limits what can pass based on electrical charge
Basil lamina
The outermost layer of the glomerular filter creates filtration slits that limit what can pass through based on size
Pedicel of the podocytes
The fluid that leaves the blood in the glomerulus and enters the Bowman capsule
Filtrate
What can get through the filter and what can not list organic molecules that get filtered out of the blood and become part of the filtrate
Amino acids, glucose, lipids and nitrogenous waste
Which category of molecules in the plasma is prevented from passing through the glomerular filtrate
Protein
Which major component of blood ( plasma versus formed/ cellular elements)contains substances that are completely prevented from passing through the glomerular filter
Cellular elements
Most reabsorption starts here
Proximal tubule 65%
This is the only location in the tubule where organic molecules can be reabsorbed
Proximal tubule
Only water is reabsorbed in this segment of the nephron
Descending limb of the loop of Henley
Only ions are reabsorbed in this segment of the nephron
Ascending limb of the loop of Henle
The kidneys produce _____ liters of filtrate every day
Only _____ leaders is excreted from the body daily
1) 180
2) 1-2 liters
A minimum of _____ milliliters per day must be excreted to remove waste product from metabolism this is called:
400
Obligatory water loss
Water will move across a membrane to a location with more of these
Osmotically active solutes
If only water is being reabsorbed from the descending limb what happens to the concentration or osmolarity of the filtrate from the top of the limb to the bottom
Filtrate becomes more concentrated with osmotically active solute
If only ions are being reabsorbed from the ascending limb what happens to the concentration or osmolarity of the filtrate from the bottom of the loop to the top
It becomes more diluted mixing solutes with water
Which must move first water from the descending limb or ions from the ascending limb and why
Ions from the ascending limb