Lab 1 Flashcards
In the rate-determining step of an electrophilic addition reaction, the ————— acts as a nucleophile
alkene
In the rate-determining step of an electrophilic addition reaction, the ————— attack the pi bond
electrons
In the rate-determining step of an electrophilic addition reaction, the electrophile is attacked by the electrons to generate a —————
carbocation intermediate
In the rate-determining step of an electrophilic substitution reaction, the aromatic ring acts as a ———-
nucleophile
In an electrophilic aromatic substitution reaction, substituents on benzene can influence the
reaction rate and position where substitution occurs
The presence of an electron———-group will increase the reaction rate.
donating
An -OH substituent on a ring is considered——— . It will result in primarily ————-products.
activating, ortho and para
A carboxylic acid substituent on a ring is considered——–It will result in primarily——–products.
deactivating, meta
Nitration reactions are examples of
electrophilic aromatic substitution reactions
The nitronium ion forms from the reaction of
sulfuric acid and nitric acid
You will characterize your nitration product using
TLC, melting point, mixed melting point
What solvent will you use to dissolve your product prior to spotting it on your TLC plate?
acetone
You should add your nitrating solution to methyl benzoate at a rate of ——drops per minute over a period of ——minutes.
two, fifteen
Based on your knowledge of the effects of substituents on electrophilic aromatic substitution reactions, the product of the nitration of methyl benzoate should be primarily
methyl m-nitrobenzoate
T/F: Benzene undergoes electrophilic addition reactions.
False
