L9 RNA Flashcards
Who provided the first indication that DNA was the inheritance factor?
Oswald T. Avery
What experiment provided evidence for the semi-conservative model of DNA replication?
The Meselson-Stahl experiment
What are the four nucleotide bases in DNA?
Adenine (A), Thymine (T), Cytosine (C), and Guanine (G)
What is the difference between the leading and lagging strands during DNA replication?
The leading strand is synthesized continuously, while the lagging strand is synthesized in short fragments (Okazaki fragments)
What enzyme is responsible for joining Okazaki fragments?
DNA ligase
What is the function of DNA primase in replication?
To synthesize short RNA primers to initiate DNA synthesis
How many base pairs are there per turn of the DNA double helix?
10 base pairs
What is the directionality of DNA strand synthesis?
5’ to 3’
What type of bonds hold the two strands of DNA together?
Hydrogen bonds between complementary base pairs
What hypothesis did Beadle and Tatum propose?
The ‘one gene-one enzyme’ hypothesis