L9 RNA Flashcards

1
Q

Who provided the first indication that DNA was the inheritance factor?

A

Oswald T. Avery

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2
Q

What experiment provided evidence for the semi-conservative model of DNA replication?

A

The Meselson-Stahl experiment

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3
Q

What are the four nucleotide bases in DNA?

A

Adenine (A), Thymine (T), Cytosine (C), and Guanine (G)

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4
Q

What is the difference between the leading and lagging strands during DNA replication?

A

The leading strand is synthesized continuously, while the lagging strand is synthesized in short fragments (Okazaki fragments)

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5
Q

What enzyme is responsible for joining Okazaki fragments?

A

DNA ligase

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6
Q

What is the function of DNA primase in replication?

A

To synthesize short RNA primers to initiate DNA synthesis

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7
Q

How many base pairs are there per turn of the DNA double helix?

A

10 base pairs

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8
Q

What is the directionality of DNA strand synthesis?

A

5’ to 3’

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9
Q

What type of bonds hold the two strands of DNA together?

A

Hydrogen bonds between complementary base pairs

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10
Q

What hypothesis did Beadle and Tatum propose?

A

The ‘one gene-one enzyme’ hypothesis

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